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A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.
Blaschke M, McKinnon R, Nguyen CH, Holzner S, Zehl M, Atanasov AG, Schelch K, Krieger S, Diaz R, Frisch R, Feistel B, Jäger W, Ecker GF, Dirsch VM, Grusch M, Zupko I, Urban E, Kopp B, Krupitza G. Blaschke M, et al. Among authors: feistel b. Mutat Res. 2015 Jul;777:79-90. doi: 10.1016/j.mrfmmm.2015.04.011. Epub 2015 May 5. Mutat Res. 2015. PMID: 25989051
Separation of anti-neoplastic activities by fractionation of a Pluchea odorata extract.
Bauer S, Singhuber J, Seelinger M, Unger C, Viola K, Vonach C, Giessrigl B, Madlener S, Stark N, Wallnofer B, Wagner KH, Fritzer-Szekeres M, Szekeres T, Diaz R, Tut F, Frisch R, Feistel B, Kopp B, Krupitza G, Popescu R. Bauer S, et al. Among authors: feistel b. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1326-36. doi: 10.2741/e336. Front Biosci (Elite Ed). 2011. PMID: 21622139 Free article.
Fractionation of an Extract of Pluchea odorata Separates a Property Indicative for the Induction of Cell Plasticity from One That Inhibits a Neoplastic Phenotype.
Seelinger M, Popescu R, Seephonkai P, Singhuber J, Giessrigl B, Unger C, Bauer S, Wagner KH, Fritzer-Szekeres M, Szekeres T, Diaz R, Tut FM, Frisch R, Feistel B, Kopp B, Krupitza G. Seelinger M, et al. Among authors: feistel b. Evid Based Complement Alternat Med. 2012;2012:701927. doi: 10.1155/2012/701927. Epub 2012 Mar 13. Evid Based Complement Alternat Med. 2012. PMID: 22474515 Free PMC article.
19 results