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A phosphotyrosine switch regulates organic cation transporters.
Sprowl JA, Ong SS, Gibson AA, Hu S, Du G, Lin W, Li L, Bharill S, Ness RA, Stecula A, Offer SM, Diasio RB, Nies AT, Schwab M, Cavaletti G, Schlatter E, Ciarimboli G, Schellens JHM, Isacoff EY, Sali A, Chen T, Baker SD, Sparreboom A, Pabla N. Sprowl JA, et al. Among authors: sali a. Nat Commun. 2016 Mar 16;7:10880. doi: 10.1038/ncomms10880. Nat Commun. 2016. PMID: 26979622 Free PMC article.
The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment.
Tran TH, Nguyen JV, Stecula A, Akutagawa J, Moorman AV, Braun BS, Sali A, Mullighan CG, Shah NP, Dai Y, Devidas M, Roberts KG, Smith CC, Loh ML. Tran TH, et al. Among authors: sali a. Haematologica. 2021 Aug 1;106(8):2242-2245. doi: 10.3324/haematol.2020.261354. Haematologica. 2021. PMID: 33626861 Free PMC article. No abstract available.
636 results