Bagh MB - Search Results

1

Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.

Chandra G, Bagh MB, Peng S, Saha A, Sarkar C, Moralle M, Zhang Z, Mukherjee AB. Chandra G, et al. Among authors: bagh mb. Hum Mol Genet. 2015 Oct 1;24(19):5416-32. doi: 10.1093/hmg/ddv266. Epub 2015 Jul 9. Hum Mol Genet. 2015. PMID: 26160911 Free PMC article.

2

Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.

Bagh MB, Peng S, Chandra G, Zhang Z, Singh SP, Pattabiraman N, Liu A, Mukherjee AB. Bagh MB, et al. Nat Commun. 2017 Mar 7;8:14612. doi: 10.1038/ncomms14612. Nat Commun. 2017. PMID: 28266544 Free PMC article.

3

Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses.

Mukherjee AB, Appu AP, Sadhukhan T, Casey S, Mondal A, Zhang Z, Bagh MB. Mukherjee AB, et al. Among authors: bagh mb. Mol Neurodegener. 2019 Jan 16;14(1):4. doi: 10.1186/s13024-018-0300-6. Mol Neurodegener. 2019. PMID: 30651094 Free PMC article. Review.

4

Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.

Sarkar C, Sadhukhan T, Bagh MB, Appu AP, Chandra G, Mondal A, Saha A, Mukherjee AB. Sarkar C, et al. Among authors: bagh mb. J Inherit Metab Dis. 2020 Sep;43(5):1082-1101. doi: 10.1002/jimd.12242. Epub 2020 Apr 27. J Inherit Metab Dis. 2020. PMID: 32279353 Free PMC article.

5

Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.

Kong E, Peng S, Chandra G, Sarkar C, Zhang Z, Bagh MB, Mukherjee AB. Kong E, et al. Among authors: bagh mb. J Biol Chem. 2013 Mar 29;288(13):9112-25. doi: 10.1074/jbc.M112.421073. Epub 2013 Feb 8. J Biol Chem. 2013. PMID: 23396970 Free PMC article.

6

Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice.

Peng S, Xu J, Pelkey KA, Chandra G, Zhang Z, Bagh MB, Yuan X, Wu LG, McBain CJ, Mukherjee AB. Peng S, et al. Among authors: bagh mb. Ann Clin Transl Neurol. 2015 Nov 6;2(12):1085-104. doi: 10.1002/acn3.261. eCollection 2015 Dec. Ann Clin Transl Neurol. 2015. PMID: 26734660 Free PMC article.

7

Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome.

Appu AP, Bagh MB, Sadhukhan T, Mondal A, Casey S, Mukherjee AB. Appu AP, et al. Among authors: bagh mb. J Inherit Metab Dis. 2019 Sep;42(5):944-954. doi: 10.1002/jimd.12106. Epub 2019 May 14. J Inherit Metab Dis. 2019. PMID: 31025705 Free PMC article.

8

In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation.

Sadhukhan T, Bagh MB, Appu AP, Mondal A, Zhang W, Liu A, Mukherjee AB. Sadhukhan T, et al. Among authors: bagh mb. J Inherit Metab Dis. 2021 Jul;44(4):1051-1069. doi: 10.1002/jimd.12379. Epub 2021 Mar 29. J Inherit Metab Dis. 2021. PMID: 33739454

9

Ablation of microRNA-155 and neuroinflammation in a mouse model of CLN1-disease.

Sadhukhan T, Bagh MB, Sadhukhan S, Appu AP, Mondal A, Iiben JR, Li T, Coon SL, Mukherjee AB. Sadhukhan T, et al. Among authors: bagh mb. Biochem Biophys Res Commun. 2021 Sep 24;571:137-144. doi: 10.1016/j.bbrc.2021.07.057. Epub 2021 Jul 26. Biochem Biophys Res Commun. 2021. PMID: 34325129

10

Ppt1-deficiency dysregulates lysosomal Ca⁺⁺ homeostasis contributing to pathogenesis in a mouse model of CLN1 disease.

Mondal A, Appu AP, Sadhukhan T, Bagh MB, Previde RM, Sadhukhan S, Stojilkovic S, Liu A, Mukherjee AB. Mondal A, et al. Among authors: bagh mb. J Inherit Metab Dis. 2022 May;45(3):635-656. doi: 10.1002/jimd.12485. Epub 2022 Mar 17. J Inherit Metab Dis. 2022. PMID: 35150145 Free PMC article.

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