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Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.
Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN. Bhatt S, et al. Among authors: church g. Cell Metab. 2015 Aug 4;22(2):239-52. doi: 10.1016/j.cmet.2015.07.015. Cell Metab. 2015. PMID: 26244933 Free PMC article.
Realizing the potential of synthetic biology.
Church GM, Elowitz MB, Smolke CD, Voigt CA, Weiss R. Church GM, et al. Nat Rev Mol Cell Biol. 2014 Apr;15(4):289-94. doi: 10.1038/nrm3767. Epub 2014 Mar 12. Nat Rev Mol Cell Biol. 2014. PMID: 24622617 Free PMC article. Review.
Rapid neurogenesis through transcriptional activation in human stem cells.
Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM. Busskamp V, et al. Mol Syst Biol. 2014 Nov 17;10(11):760. doi: 10.15252/msb.20145508. Mol Syst Biol. 2014. PMID: 25403753 Free PMC article.
Highly efficient Cas9-mediated transcriptional programming.
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM. Chavez A, et al. Nat Methods. 2015 Apr;12(4):326-8. doi: 10.1038/nmeth.3312. Epub 2015 Mar 2. Nat Methods. 2015. PMID: 25730490 Free PMC article.
In vivo gene editing in dystrophic mouse muscle and muscle stem cells.
Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. Tabebordbar M, et al. Science. 2016 Jan 22;351(6271):407-411. doi: 10.1126/science.aad5177. Epub 2015 Dec 31. Science. 2016. PMID: 26721686 Free PMC article.
A multifunctional AAV-CRISPR-Cas9 and its host response.
Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM. Chew WL, et al. Nat Methods. 2016 Oct;13(10):868-74. doi: 10.1038/nmeth.3993. Epub 2016 Sep 5. Nat Methods. 2016. PMID: 27595405 Free PMC article.
A comprehensive library of human transcription factors for cell fate engineering.
Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM. Ng AHM, et al. Among authors: church gm. Nat Biotechnol. 2021 Apr;39(4):510-519. doi: 10.1038/s41587-020-0742-6. Epub 2020 Nov 30. Nat Biotechnol. 2021. PMID: 33257861 Free PMC article.
Neuronal Cell-type Engineering by Transcriptional Activation.
Liu S, Striebel J, Pasquini G, Ng AHM, Khoshakhlagh P, Church GM, Busskamp V. Liu S, et al. Among authors: church gm. Front Genome Ed. 2021 Sep 1;3:715697. doi: 10.3389/fgeed.2021.715697. eCollection 2021. Front Genome Ed. 2021. PMID: 34713262 Free PMC article. Review.
Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers.
Kobayashi M, Kobayashi M, Odajima J, Shioda K, Hwang YS, Sasaki K, Chatterjee P, Kramme C, Kohman RE, Church GM, Loehr AR, Weiss RS, Jüppner H, Gell JJ, Lau CC, Shioda T. Kobayashi M, et al. Stem Cell Reports. 2022 Mar 8;17(3):507-521. doi: 10.1016/j.stemcr.2022.01.012. Epub 2022 Feb 10. Stem Cell Reports. 2022. PMID: 35148847 Free PMC article.
697 results