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Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.
Paradis JS, Ly S, Blondel-Tepaz É, Galan JA, Beautrait A, Scott MG, Enslen H, Marullo S, Roux PP, Bouvier M. Paradis JS, et al. Among authors: beautrait a. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5160-8. doi: 10.1073/pnas.1508836112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324936 Free PMC article.
Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.
Alexander RA, Lot I, Saha K, Abadie G, Lambert M, Decosta E, Kobayashi H, Beautrait A, Borrull A, Asnacios A, Bouvier M, Scott MGH, Marullo S, Enslen H. Alexander RA, et al. Among authors: beautrait a. Cell Mol Life Sci. 2020 Dec;77(24):5259-5279. doi: 10.1007/s00018-020-03471-5. Epub 2020 Feb 10. Cell Mol Life Sci. 2020. PMID: 32040695 Free PMC article.
Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.
Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK. Chaturvedi M, et al. Among authors: beautrait a. Trends Biochem Sci. 2018 Jul;43(7):533-546. doi: 10.1016/j.tibs.2018.04.003. Epub 2018 May 4. Trends Biochem Sci. 2018. PMID: 29735399 Free PMC article. Review.
Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, Marinier A, Laporte SA. Giubilaro J, et al. Among authors: beautrait a. Nat Commun. 2021 Aug 3;12(1):4688. doi: 10.1038/s41467-021-24968-y. Nat Commun. 2021. PMID: 34344896 Free PMC article.
Quantifying biased signaling in GPCRs using BRET-based biosensors.
Namkung Y, Radresa O, Armando S, Devost D, Beautrait A, Le Gouill C, Laporte SA. Namkung Y, et al. Among authors: beautrait a. Methods. 2016 Jan 1;92:5-10. doi: 10.1016/j.ymeth.2015.04.010. Epub 2015 Apr 15. Methods. 2016. PMID: 25890247
Identification of Allosteric Inhibitors against Active Caspase-6.
Tubeleviciute-Aydin A, Beautrait A, Lynham J, Sharma G, Gorelik A, Deny LJ, Soya N, Lukacs GL, Nagar B, Marinier A, LeBlanc AC. Tubeleviciute-Aydin A, et al. Among authors: beautrait a. Sci Rep. 2019 Apr 2;9(1):5504. doi: 10.1038/s41598-019-41930-7. Sci Rep. 2019. PMID: 30940883 Free PMC article.
17 results