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Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.
Paradis JS, Ly S, Blondel-Tepaz É, Galan JA, Beautrait A, Scott MG, Enslen H, Marullo S, Roux PP, Bouvier M. Paradis JS, et al. Among authors: galan ja. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5160-8. doi: 10.1073/pnas.1508836112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324936 Free PMC article.
Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
Zhang X, Lavoie G, Fort L, Huttlin EL, Tcherkezian J, Galan JA, Gu H, Gygi SP, Carreno S, Roux PP. Zhang X, et al. Among authors: galan ja. Mol Cell Biol. 2013 Apr;33(8):1657-70. doi: 10.1128/MCB.01353-12. Epub 2013 Feb 11. Mol Cell Biol. 2013. PMID: 23401857 Free PMC article.
Regulation of Syk by phosphorylation on serine in the linker insert.
Paris LL, Hu J, Galan J, Ong SS, Martin VA, Ma H, Tao WA, Harrison ML, Geahlen RL. Paris LL, et al. J Biol Chem. 2010 Dec 17;285(51):39844-54. doi: 10.1074/jbc.M110.164509. Epub 2010 Oct 18. J Biol Chem. 2010. PMID: 20956537 Free PMC article.
64 results