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Discovery of small molecule HIV-1 integrase dimerization inhibitors.
Tintori C, Demeulemeester J, Franchi L, Massa S, Debyser Z, Christ F, Botta M. Tintori C, et al. Among authors: botta m. Bioorg Med Chem Lett. 2012 May 1;22(9):3109-14. doi: 10.1016/j.bmcl.2012.03.064. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22483582
Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules.
Tintori C, Corona A, Esposito F, Brai A, Grandi N, Ceresola ER, Clementi M, Canducci F, Tramontano E, Botta M. Tintori C, et al. Among authors: botta m. Chembiochem. 2016 Apr 15;17(8):683-8. doi: 10.1002/cbic.201500668. Epub 2016 Mar 21. Chembiochem. 2016. PMID: 26946324
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.
Martini R, Esposito F, Corona A, Ferrarese R, Ceresola ER, Visconti L, Tintori C, Barbieri A, Calcaterra A, Iovine V, Canducci F, Tramontano E, Botta M. Martini R, et al. Among authors: botta m. Chembiochem. 2017 Feb 16;18(4):374-377. doi: 10.1002/cbic.201600592. Epub 2017 Jan 18. Chembiochem. 2017. PMID: 27992102
Novel virtual screening protocol based on the combined use of molecular modeling and electron-ion interaction potential techniques to design HIV-1 integrase inhibitors.
Tintori C, Manetti F, Veljkovic N, Perovic V, Vercammen J, Hayes S, Massa S, Witvrouw M, Debyser Z, Veljkovic V, Botta M. Tintori C, et al. Among authors: botta m. J Chem Inf Model. 2007 Jul-Aug;47(4):1536-44. doi: 10.1021/ci700078n. Epub 2007 Jul 3. J Chem Inf Model. 2007. PMID: 17608406
Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.
Pasquini S, Mugnaini C, Tintori C, Botta M, Trejos A, Arvela RK, Larhed M, Witvrouw M, Michiels M, Christ F, Debyser Z, Corelli F. Pasquini S, et al. Among authors: botta m. J Med Chem. 2008 Aug 28;51(16):5125-9. doi: 10.1021/jm8003784. Epub 2008 Jul 30. J Med Chem. 2008. PMID: 18665580
723 results