Zhang X - Search Results

1

Exploration of the linkage elements of porcupine antagonists led to potent Wnt signaling pathway inhibitors.

Dong Y, Li K, Xu Z, Ma H, Zheng J, Hu Z, He S, Wu Y, Sun Z, Luo L, Li J, Zhang H, Zhang X. Dong Y, et al. Among authors: zhang h, zhang x. Bioorg Med Chem. 2015 Nov 1;23(21):6855-68. doi: 10.1016/j.bmc.2015.09.048. Epub 2015 Oct 1. Bioorg Med Chem. 2015. PMID: 26455655

2

2,6-Diaryl-4-phenacylaminopyrimidines as potent and selective adenosine A(2A) antagonists with reduced hERG liability.

Moorjani M, Zhang X, Chen Y, Lin E, Rueter JK, Gross RS, Lanier MC, Tellew JE, Williams JP, Lechner SM, Malany S, Santos M, Ekhlassi P, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH. Moorjani M, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1269-73. doi: 10.1016/j.bmcl.2008.01.036. Epub 2008 Jan 13. Bioorg Med Chem Lett. 2008. PMID: 18249540

3

Cyclopamine, a naturally occurring alkaloid, and its analogues may find wide applications in cancer therapy.

Ma H, Li HQ, Zhang X. Ma H, et al. Among authors: zhang x. Curr Top Med Chem. 2013;13(17):2208-15. doi: 10.2174/15680266113139990153. Curr Top Med Chem. 2013. PMID: 23978132 Review.

4

Replacement of amide with bioisosteres led to a new series of potent adenosine A2A receptor antagonists.

Yang Z, Li X, Ma H, Zheng J, Zhen X, Zhang X. Yang Z, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2014 Jan 1;24(1):152-5. doi: 10.1016/j.bmcl.2013.11.051. Epub 2013 Dec 1. Bioorg Med Chem Lett. 2014. PMID: 24332624

5

Scaffold hopping approach to a new series of smoothened antagonists.

Lu W, Geng D, Sun Z, Yang Z, Ma H, Zheng J, Zhang X. Lu W, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2014 May 15;24(10):2300-4. doi: 10.1016/j.bmcl.2014.03.079. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24726807

6

Optimization of 6-heterocyclic-2-(1H-pyrazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine as potent adenosine A2A receptor antagonists for the treatment of Parkinson's disease.

Zheng J, Yang Z, Li X, Li L, Ma H, Wang M, Zhang H, Zhen X, Zhang X. Zheng J, et al. Among authors: zhang h, zhang x. ACS Chem Neurosci. 2014 Aug 20;5(8):674-82. doi: 10.1021/cn5000716. Epub 2014 Jun 23. ACS Chem Neurosci. 2014. PMID: 24922583 Free PMC article.

7

Design, synthesis, and structure--activity-relationship of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.

Ma H, Lu W, Sun Z, Luo L, Geng D, Yang Z, Li E, Zheng J, Wang M, Zhang H, Yang S, Zhang X. Ma H, et al. Among authors: zhang h, zhang x. Eur J Med Chem. 2015 Jan 7;89:721-32. doi: 10.1016/j.ejmech.2014.11.006. Epub 2014 Nov 4. Eur J Med Chem. 2015. PMID: 25462278

8

Design, synthesis and evaluation of a series of non-steroidal anti-inflammatory drug conjugates as novel neuroinflammatory inhibitors.

Xu Z, Wu J, Zheng J, Ma H, Zhang H, Zhen X, Zheng LT, Zhang X. Xu Z, et al. Among authors: zhang h, zhang x. Int Immunopharmacol. 2015 Apr;25(2):528-37. doi: 10.1016/j.intimp.2015.02.033. Epub 2015 Mar 10. Int Immunopharmacol. 2015. PMID: 25765352

9

Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitors.

Yang Z, Ma H, Sun Z, Luo L, Tian S, Zheng J, Zhang X. Yang Z, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3665-70. doi: 10.1016/j.bmcl.2015.06.049. Epub 2015 Jun 18. Bioorg Med Chem Lett. 2015. PMID: 26119500

10

Design, synthesis, and evaluation of potent Wnt signaling inhibitors featuring a fused 3-ring system.

Xu Z, Li J, Wu Y, Sun Z, Luo L, Hu Z, He S, Zheng J, Zhang H, Zhang X. Xu Z, et al. Among authors: zhang h, zhang x. Eur J Med Chem. 2016 Jan 27;108:154-165. doi: 10.1016/j.ejmech.2015.11.026. Epub 2015 Nov 22. Eur J Med Chem. 2016. PMID: 26647303

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

169,821 results

Search Page