Chen YJ - Search Results

1

The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke.

Chen YJ, Nguyen HM, Maezawa I, Grössinger EM, Garing AL, Köhler R, Jin LW, Wulff H. Chen YJ, et al. J Cereb Blood Flow Metab. 2016 Dec;36(12):2146-2161. doi: 10.1177/0271678X15611434. Epub 2015 Nov 2. J Cereb Blood Flow Metab. 2016. PMID: 26661208 Free PMC article.

2

The KCa3.1 blocker TRAM-34 reduces infarction and neurological deficit in a rat model of ischemia/reperfusion stroke.

Chen YJ, Raman G, Bodendiek S, O'Donnell ME, Wulff H. Chen YJ, et al. J Cereb Blood Flow Metab. 2011 Dec;31(12):2363-74. doi: 10.1038/jcbfm.2011.101. Epub 2011 Jul 13. J Cereb Blood Flow Metab. 2011. PMID: 21750563 Free PMC article.

3

Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger.

O'Donnell ME, Chen YJ, Lam TI, Taylor KC, Walton JH, Anderson SE. O'Donnell ME, et al. Among authors: chen yj. J Cereb Blood Flow Metab. 2013 Feb;33(2):225-34. doi: 10.1038/jcbfm.2012.160. Epub 2012 Nov 14. J Cereb Blood Flow Metab. 2013. PMID: 23149557 Free PMC article.

4

The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease.

Hua X, Deuse T, Chen YJ, Wulff H, Stubbendorff M, Köhler R, Miura H, Länger F, Reichenspurner H, Robbins RC, Schrepfer S. Hua X, et al. Among authors: chen yj. Transplantation. 2013 Jan 27;95(2):285-92. doi: 10.1097/TP.0b013e318275a2f4. Transplantation. 2013. PMID: 23325003 Free PMC article.

5

The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy.

Chen YJ, Lam J, Gregory CR, Schrepfer S, Wulff H. Chen YJ, et al. PLoS One. 2013 Nov 29;8(11):e81006. doi: 10.1371/journal.pone.0081006. eCollection 2013. PLoS One. 2013. PMID: 24312257 Free PMC article.

6

Kv1.3 in psoriatic disease: PAP-1, a small molecule inhibitor of Kv1.3 is effective in the SCID mouse psoriasis--xenograft model.

Kundu-Raychaudhuri S, Chen YJ, Wulff H, Raychaudhuri SP. Kundu-Raychaudhuri S, et al. Among authors: chen yj. J Autoimmun. 2014 Dec;55:63-72. doi: 10.1016/j.jaut.2014.07.003. Epub 2014 Aug 28. J Autoimmun. 2014. PMID: 25175978 Free PMC article.

7

The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant.

Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. Coleman N, et al. Among authors: chen yj. Neurotherapeutics. 2015 Jan;12(1):234-49. doi: 10.1007/s13311-014-0305-y. Neurotherapeutics. 2015. PMID: 25256961 Free PMC article.

8

Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke.

Chen YJ, Wallace BK, Yuen N, Jenkins DP, Wulff H, O'Donnell ME. Chen YJ, et al. Stroke. 2015 Jan;46(1):237-44. doi: 10.1161/STROKEAHA.114.007445. Epub 2014 Dec 4. Stroke. 2015. PMID: 25477223 Free PMC article.

9

Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke.

Chen YJ, Nguyen HM, Maezawa I, Jin LW, Wulff H. Chen YJ, et al. Ann Clin Transl Neurol. 2017 Dec 19;5(2):147-161. doi: 10.1002/acn3.513. eCollection 2018 Feb. Ann Clin Transl Neurol. 2017. PMID: 29468176 Free PMC article.

10

Exacerbated brain edema in a rat streptozotocin model of hyperglycemic ischemic stroke: Evidence for involvement of blood-brain barrier Na-K-Cl cotransport and Na/H exchange.

Yuen NY, Chechneva OV, Chen YJ, Tsai YC, Little LK, Dang J, Tancredi DJ, Conston J, Anderson SE, O'Donnell ME. Yuen NY, et al. Among authors: chen yj. J Cereb Blood Flow Metab. 2019 Sep;39(9):1678-1692. doi: 10.1177/0271678X18770844. Epub 2018 May 9. J Cereb Blood Flow Metab. 2019. PMID: 29739261 Free PMC article.

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