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A molecular signature of tissues with pacemaker activity in the heart and upper urinary tract involves coexpressed hyperpolarization-activated cation and T-type Ca2+ channels.
Hurtado R, Bub G, Herzlinger D. Hurtado R, et al. FASEB J. 2014 Feb;28(2):730-9. doi: 10.1096/fj.13-237289. Epub 2013 Nov 4. FASEB J. 2014. PMID: 24189942 Free PMC article.
Furthermore, we demonstrate that HCN3(+) cells coexpress T-type Ca(2+) (TTC) channels and that TTC channel inhibition with R(-)efonidipine or NNC55-0396 decreased contractile frequency in a dose-dependent manner. ...Moreover, these findings have translational applications, …
Furthermore, we demonstrate that HCN3(+) cells coexpress T-type Ca(2+) (TTC) channels and that TTC channel inhibition with R(-)efonid …
Patterning the renal vascular bed.
Herzlinger D, Hurtado R. Herzlinger D, et al. Among authors: hurtado r. Semin Cell Dev Biol. 2014 Dec;36:50-6. doi: 10.1016/j.semcdb.2014.08.002. Epub 2014 Aug 13. Semin Cell Dev Biol. 2014. PMID: 25128732 Free PMC article. Review.
Hemodynamic-dependent patterning of endothelin converting enzyme 1 expression and differentiation of impulse-conducting Purkinje fibers in the embryonic heart.
Hall CE, Hurtado R, Hewett KW, Shulimovich M, Poma CP, Reckova M, Justus C, Pennisi DJ, Tobita K, Sedmera D, Gourdie RG, Mikawa T. Hall CE, et al. Among authors: hurtado r. Development. 2004 Feb;131(3):581-92. doi: 10.1242/dev.00947. Epub 2004 Jan 7. Development. 2004. PMID: 14711873 Free article.
190 results