Blenis J - Search Results

1

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.

Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC. Mullarky E, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831078 Free PMC article.

2

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

Songyang Z, Lu KP, Kwon YT, Tsai LH, Filhol O, Cochet C, Brickey DA, Soderling TR, Bartleson C, Graves DJ, DeMaggio AJ, Hoekstra MF, Blenis J, Hunter T, Cantley LC. Songyang Z, et al. Among authors: blenis j. Mol Cell Biol. 1996 Nov;16(11):6486-93. doi: 10.1128/MCB.16.11.6486. Mol Cell Biol. 1996. PMID: 8887677 Free PMC article.

3

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene.

Watson KL, Chou MM, Blenis J, Gelbart WM, Erikson RL. Watson KL, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13694-8. doi: 10.1073/pnas.93.24.13694. Proc Natl Acad Sci U S A. 1996. PMID: 8942996 Free PMC article.

4

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway.

Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC. Manning BD, et al. Among authors: blenis j. Mol Cell. 2002 Jul;10(1):151-62. doi: 10.1016/s1097-2765(02)00568-3. Mol Cell. 2002. PMID: 12150915 Free article.

5

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. Tee AR, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. doi: 10.1073/pnas.202476899. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271141 Free PMC article.

6

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. Tee AR, et al. Among authors: blenis j. Curr Biol. 2003 Aug 5;13(15):1259-68. doi: 10.1016/s0960-9822(03)00506-2. Curr Biol. 2003. PMID: 12906785 Free article.

7

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.

Roux PP, Ballif BA, Anjum R, Gygi SP, Blenis J. Roux PP, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13489-94. doi: 10.1073/pnas.0405659101. Epub 2004 Sep 1. Proc Natl Acad Sci U S A. 2004. PMID: 15342917 Free PMC article.

8

Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1.

Zhu J, Blenis J, Yuan J. Zhu J, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6584-9. doi: 10.1073/pnas.0802785105. Epub 2008 May 1. Proc Natl Acad Sci U S A. 2008. PMID: 18451027 Free PMC article.

9

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation.

Choo AY, Yoon SO, Kim SG, Roux PP, Blenis J. Choo AY, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17414-9. doi: 10.1073/pnas.0809136105. Epub 2008 Oct 27. Proc Natl Acad Sci U S A. 2008. PMID: 18955708 Free PMC article.

10

Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply.

Choo AY, Kim SG, Vander Heiden MG, Mahoney SJ, Vu H, Yoon SO, Cantley LC, Blenis J. Choo AY, et al. Among authors: blenis j. Mol Cell. 2010 May 28;38(4):487-99. doi: 10.1016/j.molcel.2010.05.007. Mol Cell. 2010. PMID: 20513425 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

245 results

Search Page