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Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia.
López C, Bergmann AK, Paul U, Murga Penas EM, Nagel I, Betts MJ, Johansson P, Ritgen M, Baumann T, Aymerich M, Jayne S, Russell RB, Campo E, Dyer MJ, Dürig J, Siebert R. López C, et al. Among authors: durig j. Br J Haematol. 2016 Apr;173(2):265-73. doi: 10.1111/bjh.13952. Epub 2016 Feb 25. Br J Haematol. 2016. PMID: 26917488 Free article.
Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32).
Dürig J, Bug S, Klein-Hitpass L, Boes T, Jöns T, Martin-Subero JI, Harder L, Baudis M, Dührsen U, Siebert R. Dürig J, et al. Leukemia. 2007 Oct;21(10):2153-63. doi: 10.1038/sj.leu.2404877. Epub 2007 Aug 16. Leukemia. 2007. PMID: 17713554
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms.
Martin-Subero JI, Ammerpohl O, Bibikova M, Wickham-Garcia E, Agirre X, Alvarez S, Brüggemann M, Bug S, Calasanz MJ, Deckert M, Dreyling M, Du MQ, Dürig J, Dyer MJ, Fan JB, Gesk S, Hansmann ML, Harder L, Hartmann S, Klapper W, Küppers R, Montesinos-Rongen M, Nagel I, Pott C, Richter J, Román-Gómez J, Seifert M, Stein H, Suela J, Trümper L, Vater I, Prosper F, Haferlach C, Cruz Cigudosa J, Siebert R. Martin-Subero JI, et al. Among authors: durig j. PLoS One. 2009 Sep 11;4(9):e6986. doi: 10.1371/journal.pone.0006986. PLoS One. 2009. PMID: 19750229 Free PMC article.
Gene dosage effects in chronic lymphocytic leukemia.
Sellmann L, Scholtysik R, Kreuz M, Cyrull S, Tiacci E, Stanelle J, Carpinteiro A, Nückel H, Boes T, Gesk S, Siebert R, Klein-Hitpass L, Dührsen U, Dürig J, Küppers R. Sellmann L, et al. Among authors: durig j. Cancer Genet Cytogenet. 2010 Dec;203(2):149-60. doi: 10.1016/j.cancergencyto.2010.09.002. Cancer Genet Cytogenet. 2010. PMID: 21156227
Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia.
Göbel M, Eisele L, Möllmann M, Hüttmann A, Johansson P, Scholtysik R, Bergmann M, Busch R, Döhner H, Hallek M, Seiler T, Stilgenbauer S, Klein-Hitpass L, Dührsen U, Dürig J. Göbel M, et al. Among authors: durig j. PLoS One. 2013 Aug 23;8(8):e72107. doi: 10.1371/journal.pone.0072107. eCollection 2013. PLoS One. 2013. PMID: 24009671 Free PMC article.
Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia.
Bergmann AK, Schneppenheim S, Seifert M, Betts MJ, Haake A, Lopez C, Maria Murga Penas E, Vater I, Jayne S, Dyer MJ, Schrappe M, Dührsen U, Ammerpohl O, Russell RB, Küppers R, Dürig J, Siebert R. Bergmann AK, et al. Among authors: durig j. Genes Chromosomes Cancer. 2014 Apr;53(4):309-16. doi: 10.1002/gcc.22141. Epub 2014 Jan 21. Genes Chromosomes Cancer. 2014. PMID: 24446122
240 results