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Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?
Toxicol Sci. 2016 Jun;151(2):365-75. doi: 10.1093/toxsci/kfw047. Epub 2016 Mar 8.
Toxicol Sci. 2016.
PMID: 26962055
Free PMC article.
Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity.
Rose KA, Holman NS, Green AM, Andersen ME, LeCluyse EL.
Rose KA, et al. Among authors: holman ns.
J Pharm Sci. 2016 Feb;105(2):950-964. doi: 10.1016/S0022-3549(15)00192-6.
J Pharm Sci. 2016.
PMID: 26869439
Free PMC article.
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miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model.
Mosedale M, Eaddy JS, Trask OJ Jr, Holman NS, Wolf KK, LeCluyse E, Ware BR, Khetani SR, Lu J, Brock WJ, Roth SE, Watkins PB.
Mosedale M, et al. Among authors: holman ns.
Toxicol Sci. 2018 Jan 1;161(1):149-158. doi: 10.1093/toxsci/kfx206.
Toxicol Sci. 2018.
PMID: 29029277
Free PMC article.
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Hepatocyte-Derived Exosomes Promote Liver Immune Tolerance: Possible Implications for Idiosyncratic Drug-Induced Liver Injury.
Holman NS, Church RJ, Nautiyal M, Rose KA, Thacker SE, Otieno MA, Wolf KK, LeCluyse E, Watkins PB, Mosedale M.
Holman NS, et al.
Toxicol Sci. 2019 Aug 1;170(2):499-508. doi: 10.1093/toxsci/kfz112.
Toxicol Sci. 2019.
PMID: 31093666
Free PMC article.
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Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα.
Wallace BD, Betts L, Talmage G, Pollet RM, Holman NS, Redinbo MR.
Wallace BD, et al. Among authors: holman ns.
J Mol Biol. 2013 Jul 24;425(14):2561-77. doi: 10.1016/j.jmb.2013.04.012. Epub 2013 Apr 16.
J Mol Biol. 2013.
PMID: 23602807
Free PMC article.
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