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Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach.
Kajanus J, Jacobson I, Åstrand A, Olsson RI, Gran U, Björe A, Fjellström O, Davidsson Ö, Emtenäs H, Dahlén A, Löfberg B, Yuan ZQ, Sundell J, Cassel J, Gyll J, Iliefski T, Högberg Å, Lindhardt E, Malmberg J. Kajanus J, et al. Among authors: sundell j. Bioorg Med Chem Lett. 2016 Apr 15;26(8):2023-9. doi: 10.1016/j.bmcl.2016.02.081. Epub 2016 Mar 2. Bioorg Med Chem Lett. 2016. PMID: 26965854
Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5.
Olsson RI, Jacobson I, Boström J, Fex T, Björe A, Olsson C, Sundell J, Gran U, Öhrn A, Nordin A, Gyll J, Thorstensson M, Hayen A, Aplander K, Hidestål O, Jiang F, Linhardt G, Forsström E, Collins T, Sundqvist M, Lindhardt E, Åstrand A, Löfberg B. Olsson RI, et al. Among authors: sundell j. Bioorg Med Chem Lett. 2013 Feb 1;23(3):706-10. doi: 10.1016/j.bmcl.2012.11.098. Epub 2012 Dec 3. Bioorg Med Chem Lett. 2013. PMID: 23260347
Lactam sulfonamides as potent inhibitors of the Kv1.5 potassium ion channel.
Olsson RI, Jacobson I, Iliefski T, Boström J, Davidsson Ö, Fjellström O, Björe A, Olsson C, Sundell J, Gran U, Gyll J, Malmberg J, Hidestål O, Emtenäs H, Svensson T, Yuan ZQ, Strandlund G, Åstrand A, Lindhardt E, Linhardt G, Forsström E, Högberg Å, Persson F, Andersson B, Rönnborg A, Löfberg B. Olsson RI, et al. Among authors: sundell j. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1269-73. doi: 10.1016/j.bmcl.2014.01.067. Epub 2014 Jan 30. Bioorg Med Chem Lett. 2014. PMID: 24513046
Impact of Excited-State Antiaromaticity Relief in a Fundamental Benzene Photoreaction Leading to Substituted Bicyclo[3.1.0]hexenes.
Slanina T, Ayub R, Toldo J, Sundell J, Rabten W, Nicaso M, Alabugin I, Fdez Galván I, Gupta AK, Lindh R, Orthaber A, Lewis RJ, Grönberg G, Bergman J, Ottosson H. Slanina T, et al. Among authors: sundell j. J Am Chem Soc. 2020 Jun 24;142(25):10942-10954. doi: 10.1021/jacs.9b13769. Epub 2020 Jun 11. J Am Chem Soc. 2020. PMID: 32456426 Free PMC article.
215 results