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Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex.
Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE. Gustavsen A, et al. Among authors: landsem a. J Infect Dis. 2016 Jul 1;214(1):140-50. doi: 10.1093/infdis/jiw100. Epub 2016 Mar 14. J Infect Dis. 2016. PMID: 26977050 Free PMC article.
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.
Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, Bergseth G, Nymo S, Lappegård KT, Woodruff TM, Espevik T, Mollnes TE, Brekke OL. Landsem A, et al. Clin Exp Immunol. 2019 Apr;196(1):97-110. doi: 10.1111/cei.13240. Epub 2018 Dec 19. Clin Exp Immunol. 2019. PMID: 30444525 Free PMC article.
A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity.
Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE. Nilsson PH, et al. Among authors: landsem a. J Immunol. 2021 Sep 15;207(6):1641-1651. doi: 10.4049/jimmunol.2001471. Epub 2021 Aug 11. J Immunol. 2021. PMID: 34380648 Free PMC article.
Systemic inflammation in acute intermittent porphyria: a case-control study.
Storjord E, Dahl JA, Landsem A, Fure H, Ludviksen JK, Goldbeck-Wood S, Karlsen BO, Berg KS, Mollnes TE, W Nielsen E, Brekke OL. Storjord E, et al. Among authors: landsem a. Clin Exp Immunol. 2017 Mar;187(3):466-479. doi: 10.1111/cei.12899. Epub 2016 Dec 15. Clin Exp Immunol. 2017. PMID: 27859020 Free PMC article.
15 results