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Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study.
Ciccarone F, Malavolta M, Calabrese R, Guastafierro T, Bacalini MG, Reale A, Franceschi C, Capri M, Hervonen A, Hurme M, Grubeck-Loebenstein B, Koller B, Bernhardt J, Schӧn C, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé M, Moreno-Villanueva M, Sindlinger T, Bürkle A, Zampieri M, Caiafa P. Ciccarone F, et al. Aging Cell. 2016 Aug;15(4):755-65. doi: 10.1111/acel.12485. Epub 2016 May 11. Aging Cell. 2016. PMID: 27169697 Free PMC article.
MARK-AGE biomarkers of ageing.
Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R. Bürkle A, et al. Mech Ageing Dev. 2015 Nov;151:2-12. doi: 10.1016/j.mad.2015.03.006. Epub 2015 Mar 24. Mech Ageing Dev. 2015. PMID: 25818235 Free article. Review.
Zinc-Induced Metallothionein in Centenarian Offspring From a Large European Population: The MARK-AGE Project.
Giacconi R, Costarelli L, Piacenza F, Basso A, Bürkle A, Moreno-Villanueva M, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Hervonen A, Slagboom E, Ciccarone F, Zampieri M, Caiafa P, Jansen E, Dollé MET, Breusing N, Mocchegiani E, Malavolta M. Giacconi R, et al. J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):745-753. doi: 10.1093/gerona/glx192. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29045571
Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study.
Bacalini MG, Reale A, Malavolta M, Ciccarone F, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Hurme M, Slagboom PE, Breusing N, Aversano V, Tagliatesta S, Franceschi C, Blasco MA, Bürkle A, Caiafa P, Zampieri M. Bacalini MG, et al. Among authors: grubeck loebenstein b. Geroscience. 2021 Jun;43(3):1283-1302. doi: 10.1007/s11357-021-00347-9. Epub 2021 Apr 19. Geroscience. 2021. PMID: 33870444 Free PMC article.
Age, Sex, and BMI Influence on Copper, Zinc, and Their Major Serum Carrier Proteins in a Large European Population Including Nonagenarian Offspring From MARK-AGE Study.
Piacenza F, Giacconi R, Costarelli L, Basso A, Bürkle A, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Capri M, Hervonen A, Hurme M, Slagboom E, Breusing N, Mocchegiani E, Malavolta M. Piacenza F, et al. Among authors: grubeck loebenstein b. J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2097-2106. doi: 10.1093/gerona/glab134. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33983441
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains.
Kananen L, Enroth L, Raitanen J, Jylhävä J, Bürkle A, Moreno-Villanueva M, Bernhardt J, Toussaint O, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom PE, Talbot DCS, Libert C, Koskinen S, Bruunsgaard H, Hansen ÅM, Lund R, Hurme M, Jylhä M. Kananen L, et al. Among authors: grubeck loebenstein b. Sci Rep. 2021 Mar 17;11(1):6139. doi: 10.1038/s41598-021-85668-7. Sci Rep. 2021. PMID: 33731775 Free PMC article.
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death.
Brunner S, Herndler-Brandstetter D, Arnold CR, Wiegers GJ, Villunger A, Hackl M, Grillari J, Moreno-Villanueva M, Bürkle A, Grubeck-Loebenstein B. Brunner S, et al. Aging Cell. 2012 Aug;11(4):579-87. doi: 10.1111/j.1474-9726.2012.00819.x. Epub 2012 Apr 18. Aging Cell. 2012. PMID: 22435726 Free PMC article.
MARK-AGE population: From the human model to new insights.
Capri M, Moreno-Villanueva M, Cevenini E, Pini E, Scurti M, Borelli V, Palmas MG, Zoli M, Schön C, Siepelmeyer A, Bernhardt J, Fiegl S, Zondag G, de Craen AJ, Hervonen A, Hurme M, Sikora E, Gonos ES, Voutetakis K, Toussaint O, Debacq-Chainiaux F, Grubeck-Loebenstein B, Bürkle A, Franceschi C. Capri M, et al. Mech Ageing Dev. 2015 Nov;151:13-7. doi: 10.1016/j.mad.2015.03.010. Epub 2015 Apr 2. Mech Ageing Dev. 2015. PMID: 25843237 Free article. Review. No abstract available.
Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries.
Stuetz W, Weber D, Dollé ME, Jansen E, Grubeck-Loebenstein B, Fiegl S, Toussaint O, Bernhardt J, Gonos ES, Franceschi C, Sikora E, Moreno-Villanueva M, Breusing N, Grune T, Bürkle A. Stuetz W, et al. Nutrients. 2016 Sep 30;8(10):614. doi: 10.3390/nu8100614. Nutrients. 2016. PMID: 27706032 Free PMC article.
Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study.
Weinberger B, Keller M, Putzer C, Breitenberger D, Koller B, Fiegl S, Moreno-Villanueva M, Bernhardt J, Franceschi C, Voutetakis K, Gonos ES, Hurme M, Sikora E, Toussaint O, Debacq-Chainiaux F, Grune T, Breusing N, Bürkle A, Grubeck-Loebenstein B. Weinberger B, et al. Exp Gerontol. 2018 May;105:109-112. doi: 10.1016/j.exger.2017.08.037. Epub 2017 Oct 7. Exp Gerontol. 2018. PMID: 29017961
238 results