El-Khamisy SF - Search Results

1

Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1.

Elsayed W, El-Shafie L, Hassan MK, Farag MA, El-Khamisy SF. Elsayed W, et al. Sci Rep. 2016 May 25;6:26626. doi: 10.1038/srep26626. Sci Rep. 2016. PMID: 27220325 Free PMC article.

2

TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy.

Alagoz M, Wells OS, El-Khamisy SF. Alagoz M, et al. Nucleic Acids Res. 2014 Mar;42(5):3089-103. doi: 10.1093/nar/gkt1260. Epub 2013 Dec 13. Nucleic Acids Res. 2014. PMID: 24335147 Free PMC article.

3

TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.

Gómez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortés-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW. Gómez-Herreros F, et al. Nat Genet. 2014 May;46(5):516-21. doi: 10.1038/ng.2929. Epub 2014 Mar 23. Nat Genet. 2014. PMID: 24658003

4

Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan.

Meisenberg C, Gilbert DC, Chalmers A, Haley V, Gollins S, Ward SE, El-Khamisy SF. Meisenberg C, et al. Mol Cancer Ther. 2015 Feb;14(2):575-85. doi: 10.1158/1535-7163.MCT-14-0762. Epub 2014 Dec 18. Mol Cancer Ther. 2015. PMID: 25522766 Free PMC article.

5

P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane.

Hassan MK, Watari H, Mitamura T, Mohamed Z, El-Khamisy SF, Ohba Y, Sakuragi N. Hassan MK, et al. Oncoscience. 2015 Mar 23;2(3):294-308. doi: 10.18632/oncoscience.143. eCollection 2015. Oncoscience. 2015. PMID: 25897432 Free PMC article.

6

Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin.

Atteya R, Ashour ME, Ibrahim EE, Farag MA, El-Khamisy SF. Atteya R, et al. Mech Ageing Dev. 2017 Jan;161(Pt A):141-148. doi: 10.1016/j.mad.2016.04.012. Epub 2016 Jun 6. Mech Ageing Dev. 2017. PMID: 27282658 Free article.

7

Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.

Meisenberg C, Ashour ME, El-Shafie L, Liao C, Hodgson A, Pilborough A, Khurram SA, Downs JA, Ward SE, El-Khamisy SF. Meisenberg C, et al. Nucleic Acids Res. 2017 Feb 17;45(3):1159-1176. doi: 10.1093/nar/gkw1026. Nucleic Acids Res. 2017. PMID: 28180300 Free PMC article.

8

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.

Chiang SC, Meagher M, Kassouf N, Hafezparast M, McKinnon PJ, Haywood R, El-Khamisy SF. Chiang SC, et al. Sci Adv. 2017 Apr 28;3(4):e1602506. doi: 10.1126/sciadv.1602506. eCollection 2017 Apr. Sci Adv. 2017. PMID: 28508041 Free PMC article.

9

C9orf72 expansion disrupts ATM-mediated chromosomal break repair.

Walker C, Herranz-Martin S, Karyka E, Liao C, Lewis K, Elsayed W, Lukashchuk V, Chiang SC, Ray S, Mulcahy PJ, Jurga M, Tsagakis I, Iannitti T, Chandran J, Coldicott I, De Vos KJ, Hassan MK, Higginbottom A, Shaw PJ, Hautbergue GM, Azzouz M, El-Khamisy SF. Walker C, et al. Nat Neurosci. 2017 Sep;20(9):1225-1235. doi: 10.1038/nn.4604. Epub 2017 Jul 17. Nat Neurosci. 2017. PMID: 28714954 Free PMC article.

10

Studying TDP1 Function in DNA Repair.

Chiang SC, Liversidge K, El-Khamisy SF. Chiang SC, et al. Methods Mol Biol. 2018;1703:173-181. doi: 10.1007/978-1-4939-7459-7_13. Methods Mol Biol. 2018. PMID: 29177742

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

87 results

Search Page