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Novel Pyrazolo[1,5-a]pyrimidines as Translocator Protein 18 kDa (TSPO) Ligands: Synthesis, in Vitro Biological Evaluation, [(18)F]-Labeling, and in Vivo Neuroinflammation PET Images.
Damont A, Médran-Navarrete V, Cacheux F, Kuhnast B, Pottier G, Bernards N, Marguet F, Puech F, Boisgard R, Dollé F. Damont A, et al. Among authors: cacheux f. J Med Chem. 2015 Sep 24;58(18):7449-64. doi: 10.1021/acs.jmedchem.5b00932. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26280386
Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats.
Keller T, Krzyczmonik A, Forsback S, Picón FRL, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O. Keller T, et al. Among authors: cacheux f. Mol Imaging Biol. 2017 Oct;19(5):736-745. doi: 10.1007/s11307-016-1040-z. Mol Imaging Biol. 2017. PMID: 28083825 Free PMC article.
[18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease.
Keller T, López-Picón FR, Krzyczmonik A, Forsback S, Kirjavainen AK, Takkinen JS, Alzghool O, Rajander J, Teperi S, Cacheux F, Damont A, Dollé F, Rinne JO, Solin O, Haaparanta-Solin M. Keller T, et al. Among authors: cacheux f. Nucl Med Biol. 2018 Dec;67:1-9. doi: 10.1016/j.nucmedbio.2018.09.001. Epub 2018 Sep 26. Nucl Med Biol. 2018. PMID: 30317069 Free article.