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Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.
Kumar B, Garcia M, Weng L, Jung X, Murakami JL, Hu X, McDonald T, Lin A, Kumar AR, DiGiusto DL, Stein AS, Pullarkat VA, Hui SK, Carlesso N, Kuo YH, Bhatia R, Marcucci G, Chen CC. Kumar B, et al. Among authors: kumar ar. Leukemia. 2018 Mar;32(3):575-587. doi: 10.1038/leu.2017.259. Epub 2017 Aug 17. Leukemia. 2018. PMID: 28816238 Free PMC article.
Exosome-mediated microenvironment dysregulation in leukemia.
Kumar B, Garcia M, Murakami JL, Chen CC. Kumar B, et al. Biochim Biophys Acta. 2016 Mar;1863(3):464-470. doi: 10.1016/j.bbamcr.2015.09.017. Epub 2015 Sep 15. Biochim Biophys Acta. 2016. PMID: 26384870 Free article. Review.
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Zhang B, Nguyen LXT, Li L, Zhao D, Kumar B, Wu H, Lin A, Pellicano F, Hopcroft L, Su YL, Copland M, Holyoake TL, Kuo CJ, Bhatia R, Snyder DS, Ali H, Stein AS, Brewer C, Wang H, McDonald T, Swiderski P, Troadec E, Chen CC, Dorrance A, Pullarkat V, Yuan YC, Perrotti D, Carlesso N, Forman SJ, Kortylewski M, Kuo YH, Marcucci G. Zhang B, et al. Among authors: kumar b. Nat Med. 2018 May;24(4):450-462. doi: 10.1038/nm.4499. Epub 2018 Mar 5. Nat Med. 2018. PMID: 29505034 Free PMC article.
Exosomes-driven lipolysis and bone marrow niche remodeling supports leukemia expansion.
Kumar B, Orellana M, Brooks J, Madabushi SS, Vishwasrao P, Parra LE, Sanchez J, Salhotra A, Stein A, Chen CC, Marcucci G, Kumar Hui S. Kumar B, et al. Among authors: kumar hui s. Haematologica. 2020 Sep 10;106(5):1484-1488. doi: 10.3324/haematol.2019.246058. Haematologica. 2020. PMID: 33054109 Free PMC article. No abstract available.
Altered lymphopoiesis and immunodeficiency in miR-142 null mice.
Kramer NJ, Wang WL, Reyes EY, Kumar B, Chen CC, Ramakrishna C, Cantin EM, Vonderfecht SL, Taganov KD, Chau N, Boldin MP. Kramer NJ, et al. Among authors: kumar b. Blood. 2015 Jun 11;125(24):3720-30. doi: 10.1182/blood-2014-10-603951. Epub 2015 Apr 30. Blood. 2015. PMID: 25931583 Free article.
8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia.
Buettner R, Nguyen LXT, Kumar B, Morales C, Liu C, Chen LS, Pemovska T, Synold TW, Palmer J, Thompson R, Li L, Hoang DH, Zhang B, Ghoda L, Kowolik C, Kontro M, Leitch C, Wennerberg K, Yu X, Chen CC, Horne D, Gandhi V, Pullarkat V, Marcucci G, Rosen ST. Buettner R, et al. Among authors: kumar b. J Cell Physiol. 2019 Sep;234(9):16295-16303. doi: 10.1002/jcp.28294. Epub 2019 Feb 15. J Cell Physiol. 2019. PMID: 30770553 Free PMC article.
3,861 results