Letai AG - Search Results

1

Cristae remodeling causes acidification detected by integrated graphene sensor during mitochondrial outer membrane permeabilization.

Pham TD, Pham PQ, Li J, Letai AG, Wallace DC, Burke PJ. Pham TD, et al. Among authors: letai ag. Sci Rep. 2016 Oct 27;6:35907. doi: 10.1038/srep35907. Sci Rep. 2016. PMID: 27786282 Free PMC article.

2

To Prime, or Not to Prime: That Is the Question.

Potter DS, Letai A. Potter DS, et al. Cold Spring Harb Symp Quant Biol. 2016;81:131-140. doi: 10.1101/sqb.2016.81.030841. Epub 2016 Nov 3. Cold Spring Harb Symp Quant Biol. 2016. PMID: 27811212 Review.

3

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.

Kale J, Kutuk O, Brito GC, Andrews TS, Leber B, Letai A, Andrews DW. Kale J, et al. EMBO Rep. 2018 Sep;19(9):e45235. doi: 10.15252/embr.201745235. Epub 2018 Jul 9. EMBO Rep. 2018. PMID: 29987135 Free PMC article.

4

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Letai A, et al. Cancer Cell. 2002 Sep;2(3):183-92. doi: 10.1016/s1535-6108(02)00127-7. Cancer Cell. 2002. PMID: 12242151 Free article.

5

Pharmacological manipulation of Bcl-2 family members to control cell death.

Letai A. Letai A. J Clin Invest. 2005 Oct;115(10):2648-55. doi: 10.1172/JCI26250. J Clin Invest. 2005. PMID: 16200198 Free PMC article.

6

Rational design of therapeutics targeting the BCL-2 family: are some cancer cells primed for death but waiting for a final push?

Del Gaizo Moore V, Letai A. Del Gaizo Moore V, et al. Adv Exp Med Biol. 2008;615:159-75. doi: 10.1007/978-1-4020-6554-5_8. Adv Exp Med Biol. 2008. PMID: 18437895 Review.

7

Control of mitochondrial apoptosis by the Bcl-2 family.

Brunelle JK, Letai A. Brunelle JK, et al. J Cell Sci. 2009 Feb 15;122(Pt 4):437-41. doi: 10.1242/jcs.031682. J Cell Sci. 2009. PMID: 19193868 Free PMC article. Review. No abstract available.

8

Puma strikes Bax.

Letai A. Letai A. J Cell Biol. 2009 Apr 20;185(2):189-91. doi: 10.1083/jcb.200903134. J Cell Biol. 2009. PMID: 19380876 Free PMC article.

9

Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes.

Ryan JA, Brunelle JK, Letai A. Ryan JA, et al. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12895-900. doi: 10.1073/pnas.0914878107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615979 Free PMC article.

10

BH3-only proteins and their effects on cancer.

Vo TT, Letai A. Vo TT, et al. Adv Exp Med Biol. 2010;687:49-63. doi: 10.1007/978-1-4419-6706-0_3. Adv Exp Med Biol. 2010. PMID: 20919637 Free PMC article. Review.

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