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Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, De Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Hui JY, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: breslin wj. Crit Rev Toxicol. 2016 Nov;46(10):900-910. doi: 10.1080/10408444.2016.1224807. Epub 2016 Oct 19. Crit Rev Toxicol. 2016. PMID: 27848393 Free PMC article. Review.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Theunissen PT, Beken S, Beyer B, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, de Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Y Hui J, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: breslin wj. Crit Rev Toxicol. 2017 May;47(5):402-414. doi: 10.1080/10408444.2016.1224808. Epub 2016 Oct 21. Crit Rev Toxicol. 2017. PMID: 27766926
Potential seminal transport of pharmaceuticals to the conceptus.
Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE. Scialli AR, et al. Among authors: breslin wj. Reprod Toxicol. 2015 Dec;58:213-21. doi: 10.1016/j.reprotox.2015.10.015. Epub 2015 Nov 3. Reprod Toxicol. 2015. PMID: 26545974 Free article. Review.
Reprint of "Potential seminal transport of pharmaceuticals to the conceptus".
Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE. Scialli AR, et al. Among authors: breslin wj. Reprod Toxicol. 2016 Jan;59:22-30. doi: 10.1016/j.reprotox.2016.01.005. Epub 2016 Feb 6. Reprod Toxicol. 2016. PMID: 26854737 Free article. Review.
Introduction to the HESI DART Drugs in Semen Consortium.
Chen CL, Beyer BK, Breslin WJ, DeLise AM, Hui JY, Moffat GJ, Thompson KE. Chen CL, et al. Among authors: breslin wj. Reprod Toxicol. 2014 Sep;48:113-4. doi: 10.1016/j.reprotox.2014.04.007. Epub 2014 May 4. Reprod Toxicol. 2014. PMID: 24803405 No abstract available.
Birth Control in Clinical Trials: Industry Survey of Current Use Practices, Governance, and Monitoring.
Stewart J, Breslin WJ, Beyer BK, Chadwick K, De Schaepdrijver L, Desai M, Enright B, Foster W, Hui JY, Moffat GJ, Tornesi B, Van Malderen K, Wiesner L, Chen CL. Stewart J, et al. Among authors: breslin wj. Ther Innov Regul Sci. 2016 Mar;50(2):155-168. doi: 10.1177/2168479015608415. Epub 2015 Oct 8. Ther Innov Regul Sci. 2016. PMID: 27042398 Free PMC article.
Summary of the HESI consortium studies exploring circulating inhibin B as a potential biomarker of testis damage in the rat.
Chapin R, Weinbauer G, Thibodeau MS, Sonee M, Saldutti LP, Reagan WJ, Potter D, Moffit JS, Laffan S, Kim JH, Goldstein RA, Erdos Z, Enright BP, Coulson M, Breslin WJ. Chapin R, et al. Among authors: breslin wj. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):110-8. doi: 10.1002/bdrb.21041. Epub 2013 Jan 30. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23364877
Incidence and nature of testicular toxicity findings in pharmaceutical development.
Sasaki JC, Chapin RE, Hall DG, Breslin W, Moffit J, Saldutti L, Enright B, Seger M, Jarvi K, Hixon M, Mitchard T, Kim JH. Sasaki JC, et al. Birth Defects Res B Dev Reprod Toxicol. 2011 Dec;92(6):511-25. doi: 10.1002/bdrb.20338. Birth Defects Res B Dev Reprod Toxicol. 2011. PMID: 22162370 Review.
47 results