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Page 1
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, De Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Hui JY, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: harrouk w. Crit Rev Toxicol. 2016 Nov;46(10):900-910. doi: 10.1080/10408444.2016.1224807. Epub 2016 Oct 19. Crit Rev Toxicol. 2016. PMID: 27848393 Free PMC article. Review.
Micro-CT imaging: Developing criteria for examining fetal skeletons in regulatory developmental toxicology studies - A workshop report.
Solomon HM, Makris SL, Alsaid H, Bermudez O, Beyer BK, Chen A, Chen CL, Chen Z, Chmielewski G, DeLise AM, de Schaepdrijver L, Dogdas B, French J, Harrouk W, Helfgott J, Henkelman RM, Hesterman J, Hew KW, Hoberman A, Lo CW, McDougal A, Minck DR, Scott L, Stewart J, Sutherland V, Tatiparthi AK, Winkelmann CT, Wise LD, Wood SL, Ying X. Solomon HM, et al. Among authors: harrouk w. Regul Toxicol Pharmacol. 2016 Jun;77:100-8. doi: 10.1016/j.yrtph.2016.02.018. Epub 2016 Feb 27. Regul Toxicol Pharmacol. 2016. PMID: 26930635 Free article.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Theunissen PT, Beken S, Beyer B, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, de Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Y Hui J, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: harrouk w. Crit Rev Toxicol. 2017 May;47(5):402-414. doi: 10.1080/10408444.2016.1224808. Epub 2016 Oct 21. Crit Rev Toxicol. 2017. PMID: 27766926
Current and future needs for developmental toxicity testing.
Makris SL, Kim JH, Ellis A, Faber W, Harrouk W, Lewis JM, Paule MG, Seed J, Tassinari M, Tyl R. Makris SL, et al. Among authors: harrouk w. Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):384-94. doi: 10.1002/bdrb.20335. Epub 2011 Sep 15. Birth Defects Res B Dev Reprod Toxicol. 2011. PMID: 21922641 Review.
ILSI/HESI maternal toxicity workshop summary: maternal toxicity and its impact on study design and data interpretation.
Beyer BK, Chernoff N, Danielsson BR, Davis-Bruno K, Harrouk W, Hood RD, Janer G, Liminga UW, Kim JH, Rocca M, Rogers J, Scialli AR. Beyer BK, et al. Among authors: harrouk w. Birth Defects Res B Dev Reprod Toxicol. 2011 Feb;92(1):36-51. doi: 10.1002/bdrb.20281. Epub 2010 Dec 23. Birth Defects Res B Dev Reprod Toxicol. 2011. PMID: 21312321
A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens.
Felter SP, Conolly RB, Bercu JP, Bolger PM, Boobis AR, Bos PM, Carthew P, Doerrer NG, Goodman JI, Harrouk WA, Kirkland DJ, Lau SS, Llewellyn GC, Preston RJ, Schoeny R, Schnatter AR, Tritscher A, van Velsen F, Williams GM. Felter SP, et al. Crit Rev Toxicol. 2011 Jul;41(6):507-44. doi: 10.3109/10408444.2011.552063. Epub 2011 May 18. Crit Rev Toxicol. 2011. PMID: 21591905 Review.
An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs).
Avila AM, Bebenek I, Bonzo JA, Bourcier T, Davis Bruno KL, Carlson DB, Dubinion J, Elayan I, Harrouk W, Lee SL, Mendrick DL, Merrill JC, Peretz J, Place E, Saulnier M, Wange RL, Yao J, Zhao D, Brown PC. Avila AM, et al. Among authors: harrouk w. Regul Toxicol Pharmacol. 2020 Jul;114:104662. doi: 10.1016/j.yrtph.2020.104662. Epub 2020 Apr 20. Regul Toxicol Pharmacol. 2020. PMID: 32325112
Nonclinical aspects of venous thrombosis in pregnancy.
Struble E, Harrouk W, DeFelice A, Tesfamariam B. Struble E, et al. Among authors: harrouk w. Birth Defects Res C Embryo Today. 2015 Sep;105(3):190-200. doi: 10.1002/bdrc.21111. Epub 2015 Sep 25. Birth Defects Res C Embryo Today. 2015. PMID: 26404176 Free PMC article. Review.
Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone.
Nakamura N, Vijay V, Desai VG, Hansen DK, Han T, Chang CW, Chen YC, Harrouk W, McIntyre B, Foster PM, Fuscoe JC, Inselman AL. Nakamura N, et al. Among authors: harrouk w. Reprod Toxicol. 2018 Dec;82:111-123. doi: 10.1016/j.reprotox.2018.10.001. Epub 2018 Oct 11. Reprod Toxicol. 2018. PMID: 30316929 Free PMC article.
26 results