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Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury.
Poppelaars F, van Werkhoven MB, Kotimaa J, Veldhuis ZJ, Ausema A, Broeren SGM, Damman J, Hempel JC, Leuvenink HGD, Daha MR, van Son WJ, van Kooten C, van Os RP, Hillebrands JL, Seelen MA. Poppelaars F, et al. FASEB J. 2017 Jul;31(7):3193-3204. doi: 10.1096/fj.201601218R. Epub 2017 Apr 10. FASEB J. 2017. PMID: 28396344
They further show that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.-Poppelaars, F., van Werkhoven, M. B., Kotimaa, J., Veldhuis, Z. J., Ausema, A., Broeren, S. ...
They further show that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.-Poppe
Complement in renal transplantation: The road to translation.
Jager NM, Poppelaars F, Daha MR, Seelen MA. Jager NM, et al. Among authors: poppelaars f. Mol Immunol. 2017 Sep;89:22-35. doi: 10.1016/j.molimm.2017.05.014. Epub 2017 May 27. Mol Immunol. 2017. PMID: 28558950 Review.
The Complement System in Dialysis: A Forgotten Story?
Poppelaars F, Faria B, Gaya da Costa M, Franssen CFM, van Son WJ, Berger SP, Daha MR, Seelen MA. Poppelaars F, et al. Front Immunol. 2018 Jan 25;9:71. doi: 10.3389/fimmu.2018.00071. eCollection 2018. Front Immunol. 2018. PMID: 29422906 Free PMC article. Review.
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