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Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors.
Bioorg Med Chem Lett. 2017 Feb 1;27(3):679-687. doi: 10.1016/j.bmcl.2016.11.004. Epub 2016 Nov 2.
Bioorg Med Chem Lett. 2017.
PMID: 28017532
Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration.
Perry MWD, Björhall K, Bonn B, Carlsson J, Chen Y, Eriksson A, Fredlund L, Hao H, Holden NS, Karabelas K, Lindmark H, Liu F, Pemberton N, Petersen J, Rodrigo Blomqvist S, Smith RW, Svensson T, Terstiege I, Tyrchan C, Yang W, Zhao S, Öster L.
Perry MWD, et al. Among authors: terstiege i.
J Med Chem. 2017 Jun 22;60(12):5057-5071. doi: 10.1021/acs.jmedchem.7b00401. Epub 2017 Jun 7.
J Med Chem. 2017.
PMID: 28520415
Free article.
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Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors.
Degorce SL, Aagaard A, Anjum R, Cumming IA, Diène CR, Fallan C, Johnson T, Leuchowius KJ, Orton AL, Pearson S, Robb GR, Rosen A, Scarfe GB, Scott JS, Smith JM, Steward OR, Terstiege I, Tucker MJ, Turner P, Wilkinson SD, Wrigley GL, Xue Y.
Degorce SL, et al. Among authors: terstiege i.
Bioorg Med Chem. 2020 Dec 1;28(23):115815. doi: 10.1016/j.bmc.2020.115815. Epub 2020 Oct 15.
Bioorg Med Chem. 2020.
PMID: 33091850
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Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations.
Shamovsky I, Ripa L, Narjes F, Bonn B, Schiesser S, Terstiege I, Tyrchan C.
Shamovsky I, et al. Among authors: terstiege i.
J Med Chem. 2021 Jun 24;64(12):8545-8563. doi: 10.1021/acs.jmedchem.1c00514. Epub 2021 Jun 10.
J Med Chem. 2021.
PMID: 34110134
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Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C-H Activation.
Tomberg A, Muratore MÉ, Johansson MJ, Terstiege I, Sköld C, Norrby PO.
Tomberg A, et al. Among authors: terstiege i.
iScience. 2019 Oct 25;20:373-391. doi: 10.1016/j.isci.2019.09.035. Epub 2019 Sep 27.
iScience. 2019.
PMID: 31614320
Free PMC article.
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Stille couplings catalytic in tin: the "Sn-O" approach.
Gallagher WP, Terstiege I, Maleczka RE Jr.
Gallagher WP, et al. Among authors: terstiege i.
J Am Chem Soc. 2001 Apr 11;123(14):3194-204. doi: 10.1021/ja0035295.
J Am Chem Soc. 2001.
PMID: 11457053
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A new approach for the generation and reaction of organotin hydrides: the development of reactions catalytic in Tin.
Terstiege I I, Maleczka RE Jr.
Terstiege I I, et al.
J Org Chem. 2000 Feb 11;65(3):930. doi: 10.1021/jo9940143.
J Org Chem. 2000.
PMID: 10814034
No abstract available.
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