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PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Among authors: baggen j. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.
Sun L, Meijer A, Froeyen M, Zhang L, Thibaut HJ, Baggen J, George S, Vernachio J, van Kuppeveld FJ, Leyssen P, Hilgenfeld R, Neyts J, Delang L. Sun L, et al. Among authors: baggen j. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. doi: 10.1128/AAC.01375-15. Epub 2015 Sep 14. Antimicrob Agents Chemother. 2015. PMID: 26369972 Free PMC article.
Sialic acid-dependent cell entry of human enterovirus D68.
Liu Y, Sheng J, Baggen J, Meng G, Xiao C, Thibaut HJ, van Kuppeveld FJ, Rossmann MG. Liu Y, et al. Among authors: baggen j. Nat Commun. 2015 Nov 13;6:8865. doi: 10.1038/ncomms9865. Nat Commun. 2015. PMID: 26563423 Free PMC article.
Enterovirus D68 receptor requirements unveiled by haploid genetics.
Baggen J, Thibaut HJ, Staring J, Jae LT, Liu Y, Guo H, Slager JJ, de Bruin JW, van Vliet AL, Blomen VA, Overduin P, Sheng J, de Haan CA, de Vries E, Meijer A, Rossmann MG, Brummelkamp TR, van Kuppeveld FJ. Baggen J, et al. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1399-404. doi: 10.1073/pnas.1524498113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787879 Free PMC article.
Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.
Baggen J, Hurdiss DL, Zocher G, Mistry N, Roberts RW, Slager JJ, Guo H, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM. Baggen J, et al. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):397-402. doi: 10.1073/pnas.1713284115. Epub 2017 Dec 28. Proc Natl Acad Sci U S A. 2018. PMID: 29284752 Free PMC article.
Bypassing pan-enterovirus host factor PLA2G16.
Baggen J, Liu Y, Lyoo H, van Vliet ALW, Wahedi M, de Bruin JW, Roberts RW, Overduin P, Meijer A, Rossmann MG, Thibaut HJ, van Kuppeveld FJM. Baggen J, et al. Nat Commun. 2019 Jul 18;10(1):3171. doi: 10.1038/s41467-019-11256-z. Nat Commun. 2019. PMID: 31320648 Free PMC article.
44 results