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Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.
Zawistowski JS, Bevill SM, Goulet DR, Stuhlmiller TJ, Beltran AS, Olivares-Quintero JF, Singh D, Sciaky N, Parker JS, Rashid NU, Chen X, Duncan JS, Whittle MC, Angus SP, Velarde SH, Golitz BT, He X, Santos C, Darr DB, Gallagher K, Graves LM, Perou CM, Carey LA, Earp HS, Johnson GL. Zawistowski JS, et al. Among authors: earp hs. Cancer Discov. 2017 Mar;7(3):302-321. doi: 10.1158/2159-8290.CD-16-0653. Epub 2017 Jan 20. Cancer Discov. 2017. PMID: 28108460 Free PMC article. Clinical Trial.
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Duncan JS, Whittle MC, Nakamura K, Abell AN, Midland AA, Zawistowski JS, Johnson NL, Granger DA, Jordan NV, Darr DB, Usary J, Kuan PF, Smalley DM, Major B, He X, Hoadley KA, Zhou B, Sharpless NE, Perou CM, Kim WY, Gomez SM, Chen X, Jin J, Frye SV, Earp HS, Graves LM, Johnson GL. Duncan JS, et al. Among authors: earp hs. Cell. 2012 Apr 13;149(2):307-21. doi: 10.1016/j.cell.2012.02.053. Cell. 2012. PMID: 22500798 Free PMC article.
Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains.
Stuhlmiller TJ, Miller SM, Zawistowski JS, Nakamura K, Beltran AS, Duncan JS, Angus SP, Collins KA, Granger DA, Reuther RA, Graves LM, Gomez SM, Kuan PF, Parker JS, Chen X, Sciaky N, Carey LA, Earp HS, Jin J, Johnson GL. Stuhlmiller TJ, et al. Among authors: earp hs. Cell Rep. 2015 Apr 21;11(3):390-404. doi: 10.1016/j.celrep.2015.03.037. Epub 2015 Apr 9. Cell Rep. 2015. PMID: 25865888 Free PMC article.
Adaptive reprogramming of the breast cancer kinome.
Stuhlmiller TJ, Earp HS, Johnson GL. Stuhlmiller TJ, et al. Among authors: earp hs. Clin Pharmacol Ther. 2014 Apr;95(4):413-5. doi: 10.1038/clpt.2014.8. Epub 2014 Jan 10. Clin Pharmacol Ther. 2014. PMID: 24413269 Free PMC article. Review.
Defining the expressed breast cancer kinome.
Midland AA, Whittle MC, Duncan JS, Abell AN, Nakamura K, Zawistowski JS, Carey LA, Earp HS 3rd, Graves LM, Gomez SM, Johnson GL. Midland AA, et al. Among authors: earp hs 3rd. Cell Res. 2012 Apr;22(4):620-3. doi: 10.1038/cr.2012.25. Epub 2012 Feb 7. Cell Res. 2012. PMID: 22310242 Free PMC article. No abstract available.
FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036.
Angus SP, Stuhlmiller TJ, Mehta G, Bevill SM, Goulet DR, Olivares-Quintero JF, East MP, Tanioka M, Zawistowski JS, Singh D, Sciaky N, Chen X, He X, Rashid NU, Chollet-Hinton L, Fan C, Soloway MG, Spears PA, Jefferys S, Parker JS, Gallagher KK, Forero-Torres A, Krop IE, Thompson AM, Murthy R, Gatza ML, Perou CM, Earp HS, Carey LA, Johnson GL. Angus SP, et al. Among authors: earp hs. NPJ Breast Cancer. 2021 May 12;7(1):51. doi: 10.1038/s41523-021-00258-0. NPJ Breast Cancer. 2021. PMID: 33980863 Free PMC article.
Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications.
Allott EH, Shan Y, Chen M, Sun X, Garcia-Recio S, Kirk EL, Olshan AF, Geradts J, Earp HS, Carey LA, Perou CM, Pfeiffer RM, Anderson WF, Troester MA. Allott EH, et al. Among authors: earp hs. Breast Cancer Res Treat. 2020 Jan;179(1):185-195. doi: 10.1007/s10549-019-05442-2. Epub 2019 Sep 18. Breast Cancer Res Treat. 2020. PMID: 31535320 Free PMC article.
212 results