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Exploring protein sequence-function landscapes.
Starr TN, Thornton JW. Starr TN, et al. Among authors: thornton jw. Nat Biotechnol. 2017 Feb 8;35(2):125-126. doi: 10.1038/nbt.3786. Nat Biotechnol. 2017. PMID: 28178247 Free PMC article. No abstract available.
Epistasis in protein evolution.
Starr TN, Thornton JW. Starr TN, et al. Among authors: thornton jw. Protein Sci. 2016 Jul;25(7):1204-18. doi: 10.1002/pro.2897. Epub 2016 Feb 28. Protein Sci. 2016. PMID: 26833806 Free PMC article. Review.
A hydrophobic ratchet entrenches molecular complexes.
Hochberg GKA, Liu Y, Marklund EG, Metzger BPH, Laganowsky A, Thornton JW. Hochberg GKA, et al. Among authors: thornton jw. Nature. 2020 Dec;588(7838):503-508. doi: 10.1038/s41586-020-3021-2. Epub 2020 Dec 9. Nature. 2020. PMID: 33299178 Free PMC article.
Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
Hudson WH, Kossmann BR, de Vera IM, Chuo SW, Weikum ER, Eick GN, Thornton JW, Ivanov IN, Kojetin DJ, Ortlund EA. Hudson WH, et al. Among authors: thornton jw. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):326-31. doi: 10.1073/pnas.1518960113. Epub 2015 Dec 29. Proc Natl Acad Sci U S A. 2016. PMID: 26715749 Free PMC article.
109 results