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Page 1
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.
Foley TM, Payne SN, Pasch CA, Yueh AE, Van De Hey DR, Korkos DP, Clipson L, Maher ME, Matkowskyj KA, Newton MA, Deming DA. Foley TM, et al. Among authors: clipson l. Mol Cancer Res. 2017 Feb 9;15(3):317-327. doi: 10.1158/1541-7786.MCR-16-0256. Online ahead of print. Mol Cancer Res. 2017. PMID: 28184015 Free PMC article.
Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.
Hadac JN, Leystra AA, Paul Olson TJ, Maher ME, Payne SN, Yueh AE, Schwartz AR, Albrecht DM, Clipson L, Pasch CA, Matkowskyj KA, Halberg RB, Deming DA. Hadac JN, et al. Among authors: clipson l. Cancer Prev Res (Phila). 2015 Oct;8(10):952-61. doi: 10.1158/1940-6207.CAPR-15-0003. Epub 2015 Aug 14. Cancer Prev Res (Phila). 2015. PMID: 26276752 Free PMC article.
MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers.
Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA. Fricke SL, et al. Among authors: clipson l. Mol Cancer Ther. 2019 Feb;18(2):346-355. doi: 10.1158/1535-7163.MCT-18-0510. Epub 2018 Nov 13. Mol Cancer Ther. 2019. PMID: 30425131 Free PMC article.
Mice expressing activated PI3K rapidly develop advanced colon cancer.
Leystra AA, Deming DA, Zahm CD, Farhoud M, Olson TJ, Hadac JN, Nettekoven LA, Albrecht DM, Clipson L, Sullivan R, Washington MK, Torrealba JR, Weichert JP, Halberg RB. Leystra AA, et al. Among authors: clipson l. Cancer Res. 2012 Jun 15;72(12):2931-6. doi: 10.1158/0008-5472.CAN-11-4097. Epub 2012 Apr 23. Cancer Res. 2012. PMID: 22525701 Free PMC article.
mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Deming DA, Leystra AA, Farhoud M, Nettekoven L, Clipson L, Albrecht D, Washington MK, Sullivan R, Weichert JP, Halberg RB. Deming DA, et al. Among authors: clipson l. PLoS One. 2013 Apr 9;8(4):e60709. doi: 10.1371/journal.pone.0060709. Print 2013. PLoS One. 2013. PMID: 23593290 Free PMC article.
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.
Yueh AE, Payne SN, Leystra AA, Van De Hey DR, Foley TM, Pasch CA, Clipson L, Matkowskyj KA, Deming DA. Yueh AE, et al. Among authors: clipson l. PLoS One. 2016 Feb 10;11(2):e0148730. doi: 10.1371/journal.pone.0148730. eCollection 2016. PLoS One. 2016. PMID: 26863299 Free PMC article.
Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer.
Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F. Hope C, et al. Among authors: clipson l. J Immunol. 2017 Sep 1;199(5):1933-1941. doi: 10.4049/jimmunol.1700529. Epub 2017 Jul 28. J Immunol. 2017. PMID: 28754680 Free PMC article.
Molecular Profiles Guide Colorectal Cancer Treatment.
Kratz JD, Turk AA, Sievers CK, Clipson L, Matkowskyj KA, Deming DA. Kratz JD, et al. Among authors: clipson l. Fed Pract. 2016 May;33(Suppl 4):50S-53S. Fed Pract. 2016. PMID: 30766219 Free PMC article.
53 results