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EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
Srivatsa S, Paul MC, Cardone C, Holcmann M, Amberg N, Pathria P, Diamanti MA, Linder M, Timelthaler G, Dienes HP, Kenner L, Wrba F, Prager GW, Rose-John S, Eferl R, Liguori G, Botti G, Martinelli E, Greten FR, Ciardiello F, Sibilia M. Srivatsa S, et al. Among authors: pathria p. Gastroenterology. 2017 Jul;153(1):178-190.e10. doi: 10.1053/j.gastro.2017.03.053. Epub 2017 Apr 9. Gastroenterology. 2017. PMID: 28400195 Free PMC article.
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, Müller M, Strobl B, Casanova E, Bayer E, Mohr T, Stöckl J, Friedrich K, Eferl R. Crnčec I, et al. Among authors: pathria p. Mol Oncol. 2018 Apr;12(4):514-528. doi: 10.1002/1878-0261.12178. Epub 2018 Feb 20. Mol Oncol. 2018. PMID: 29419930 Free PMC article.
Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice.
Pathria P, Gotthardt D, Prchal-Murphy M, Putz EM, Holcmann M, Schlederer M, Grabner B, Crncec I, Svinka J, Musteanu M, Hoffmann T, Filipits M, Berger W, Poli V, Kenner L, Bilban M, Casanova E, Müller M, Strobl B, Bayer E, Mohr T, Sexl V, Eferl R. Pathria P, et al. Oncoimmunology. 2015 Jan 22;4(4):e998529. doi: 10.1080/2162402X.2014.998529. eCollection 2015 Apr. Oncoimmunology. 2015. PMID: 26137415 Free PMC article.
Targeting Tumor-Associated Macrophages in Cancer.
Pathria P, Louis TL, Varner JA. Pathria P, et al. Trends Immunol. 2019 Apr;40(4):310-327. doi: 10.1016/j.it.2019.02.003. Epub 2019 Mar 17. Trends Immunol. 2019. PMID: 30890304 Review.
Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression.
Wettersten HI, Weis SM, Pathria P, Von Schalscha T, Minami T, Varner JA, Cheresh DA. Wettersten HI, et al. Among authors: pathria p. Cancer Res. 2019 Oct 1;79(19):5048-5059. doi: 10.1158/0008-5472.CAN-19-1246. Epub 2019 Aug 15. Cancer Res. 2019. PMID: 31416839 Free PMC article.
Integrin CD11b activation drives anti-tumor innate immunity.
Schmid MC, Khan SQ, Kaneda MM, Pathria P, Shepard R, Louis TL, Anand S, Woo G, Leem C, Faridi MH, Geraghty T, Rajagopalan A, Gupta S, Ahmed M, Vazquez-Padron RI, Cheresh DA, Gupta V, Varner JA. Schmid MC, et al. Among authors: pathria p. Nat Commun. 2018 Dec 19;9(1):5379. doi: 10.1038/s41467-018-07387-4. Nat Commun. 2018. PMID: 30568188 Free PMC article.