Ott M - Search Results

1

SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency.

Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. Boehm D, et al. Among authors: ott m. Cell Host Microbe. 2017 May 10;21(5):569-579.e6. doi: 10.1016/j.chom.2017.04.011. Cell Host Microbe. 2017. PMID: 28494238 Free PMC article.

2

SIRT1 regulates HIV transcription via Tat deacetylation.

Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. Pagans S, et al. Among authors: ott m. PLoS Biol. 2005 Feb;3(2):e41. doi: 10.1371/journal.pbio.0030041. Epub 2005 Feb 8. PLoS Biol. 2005. PMID: 15719057 Free PMC article.

3

The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.

Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. Mahmoudi T, et al. Among authors: ott m. J Biol Chem. 2006 Jul 21;281(29):19960-8. doi: 10.1074/jbc.M603336200. Epub 2006 May 10. J Biol Chem. 2006. PMID: 16687403 Free article.

4

Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation.

Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. Kwon HS, et al. Among authors: ott m. Cell Host Microbe. 2008 Mar 13;3(3):158-67. doi: 10.1016/j.chom.2008.02.002. Cell Host Microbe. 2008. PMID: 18329615 Free PMC article.

5

The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.

Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. Pagans S, et al. Among authors: ott m. Cell Host Microbe. 2010 Mar 18;7(3):234-44. doi: 10.1016/j.chom.2010.02.005. Cell Host Microbe. 2010. PMID: 20227666 Free PMC article.

6

Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies.

Pagans S, Sakane N, Schnölzer M, Ott M. Pagans S, et al. Among authors: ott m. Methods. 2011 Jan;53(1):91-6. doi: 10.1016/j.ymeth.2010.07.001. Epub 2010 Jul 6. Methods. 2011. PMID: 20615470 Free PMC article.

7

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).

Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. Sakane N, et al. Among authors: ott m. PLoS Pathog. 2011 Aug;7(8):e1002184. doi: 10.1371/journal.ppat.1002184. Epub 2011 Aug 18. PLoS Pathog. 2011. PMID: 21876670 Free PMC article.

8

The control of HIV transcription: keeping RNA polymerase II on track.

Ott M, Geyer M, Zhou Q. Ott M, et al. Cell Host Microbe. 2011 Nov 17;10(5):426-35. doi: 10.1016/j.chom.2011.11.002. Cell Host Microbe. 2011. PMID: 22100159 Free PMC article. Review.

9

Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis.

Webster B, Wissing S, Herker E, Ott M, Greene WC. Webster B, et al. Among authors: ott m. J Virol. 2013 Jan;87(1):581-96. doi: 10.1128/JVI.01047-12. Epub 2012 Oct 24. J Virol. 2013. PMID: 23097449 Free PMC article.

10

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. Boehm D, et al. Among authors: ott m. Cell Cycle. 2013 Feb 1;12(3):452-62. doi: 10.4161/cc.23309. Epub 2012 Feb 1. Cell Cycle. 2013. PMID: 23255218 Free PMC article.

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