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Sparse redundancy analysis of high-dimensional genetic and genomic data.
Csala A, Voorbraak FPJM, Zwinderman AH, Hof MH. Csala A, et al. Bioinformatics. 2017 Oct 15;33(20):3228-3234. doi: 10.1093/bioinformatics/btx374. Bioinformatics. 2017. PMID: 28605402
The existing theoretical framework, based on Ridge penalization, is suboptimal, since it includes all variables in the analysis. As a solution, we propose to use Elastic Net penalization in an iterative RDA framework to obtain a sparse solution. ...AVAILABILITY AND …
The existing theoretical framework, based on Ridge penalization, is suboptimal, since it includes all variables in the analysis. As a …
Gonadal androgens are associated with decreased type I interferon production by plasmacytoid dendritic cells and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents.
Sampson OL, Jay C, Adland E, Csala A, Lim N, Ebbrecht SM, Gilligan LC, Taylor AE, George SS, Longet S, Jones LC, Barnes E, Frater J, Klenerman P, Dunachie S, Carrol M, Hawley J, Arlt W, Groll A, Goulder P. Sampson OL, et al. Among authors: csala a. Front Immunol. 2024 Feb 28;15:1329805. doi: 10.3389/fimmu.2024.1329805. eCollection 2024. Front Immunol. 2024. PMID: 38481993 Free PMC article.
Age- and sex-specific differences in immune responses to BNT162b2 COVID-19 and live-attenuated influenza vaccines in UK adolescents.
Jay C, Adland E, Csala A, Lim N, Longet S, Ogbe A, Ratcliff J, Sampson O, Thompson CP, Turtle L, Barnes E, Dunachie S, Klenerman P, Carroll M, Goulder P. Jay C, et al. Among authors: csala a. Front Immunol. 2023 Oct 6;14:1248630. doi: 10.3389/fimmu.2023.1248630. eCollection 2023. Front Immunol. 2023. PMID: 37942333 Free PMC article.
Cellular immunity to SARS-CoV-2 following intrafamilial exposure in seronegative family members.
Jay C, Adland E, Csala A, Dold C, Edmans M, Hackstein CP, Jamsen A, Lim N, Longet S, Ogbe A, Sampson O, Skelly D, Spiller OB, Stafford L, Thompson CP, Turtle L, Barnes E, Dunachie S, Carroll M, Klenerman P, Conlon C, Goulder P, Jones LC. Jay C, et al. Among authors: csala a. Front Immunol. 2023 Aug 29;14:1248658. doi: 10.3389/fimmu.2023.1248658. eCollection 2023. Front Immunol. 2023. PMID: 37711627 Free PMC article.
Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV.
Vieira VA, Adland E, Grayson NE, Csala A, Richards F, Dacon C, Athavale R, Tsai MH, D'Souza R, Muenchhoff M, Bonsall D, Jooste P, Goulder PJR. Vieira VA, et al. Among authors: csala a. J Virol. 2022 Jan 26;96(2):e0153521. doi: 10.1128/JVI.01535-21. Epub 2021 Nov 10. J Virol. 2022. PMID: 34757843 Free PMC article.
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H; Medawar Laboratory Team; Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A; OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group; Tan TK, Schimanski L, Huang KA, Rijal P; PITCH (Protective Immunity T cells in Health Care Worker) Study Group; C-MORE/PHOSP-C Group; Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS. Skelly DT, et al. Nat Commun. 2021 Aug 17;12(1):5061. doi: 10.1038/s41467-021-25167-5. Nat Commun. 2021. PMID: 34404775 Free PMC article.
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.
Ogbe A, Kronsteiner B, Skelly DT, Pace M, Brown A, Adland E, Adair K, Akhter HD, Ali M, Ali SE, Angyal A, Ansari MA, Arancibia-Cárcamo CV, Brown H, Chinnakannan S, Conlon C, de Lara C, de Silva T, Dold C, Dong T, Donnison T, Eyre D, Flaxman A, Fletcher H, Gardner J, Grist JT, Hackstein CP, Jaruthamsophon K, Jeffery K, Lambe T, Lee L, Li W, Lim N, Matthews PC, Mentzer AJ, Moore SC, Naisbitt DJ, Ogese M, Ogg G, Openshaw P, Pirmohamed M, Pollard AJ, Ramamurthy N, Rongkard P, Rowland-Jones S, Sampson O, Screaton G, Sette A, Stafford L, Thompson C, Thomson PJ, Thwaites R, Vieira V, Weiskopf D, Zacharopoulou P; Oxford Immunology Network Covid-19 Response T Cell Consortium; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team; Turtle L, Klenerman P, Goulder P, Frater J, Barnes E, Dunachie S. Ogbe A, et al. Nat Commun. 2021 Apr 6;12(1):2055. doi: 10.1038/s41467-021-21856-3. Nat Commun. 2021. PMID: 33824342 Free PMC article.
Multivariate Statistical Methods for High-Dimensional Multiset Omics Data Analysis.
Csala A, Zwinderman AH. Csala A, et al. In: Husi H, editor. Computational Biology [Internet]. Brisbane (AU): Codon Publications; 2019 Nov 21. Chapter 5. In: Husi H, editor. Computational Biology [Internet]. Brisbane (AU): Codon Publications; 2019 Nov 21. Chapter 5. PMID: 31815402 Free Books & Documents. Review.
14 results