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Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.
de Cárcer G, Wachowicz P, Martínez-Martínez S, Oller J, Méndez-Barbero N, Escobar B, González-Loyola A, Takaki T, El Bakkali A, Cámara JA, Jiménez-Borreguero LJ, Bustelo XR, Cañamero M, Mulero F, de Los Ángeles Sevilla M, Montero MJ, Redondo JM, Malumbres M. de Cárcer G, et al. Among authors: mulero f. Nat Med. 2017 Aug;23(8):964-974. doi: 10.1038/nm.4364. Epub 2017 Jul 10. Nat Med. 2017. PMID: 28692064
Pten positively regulates brown adipose function, energy expenditure, and longevity.
Ortega-Molina A, Efeyan A, Lopez-Guadamillas E, Muñoz-Martin M, Gómez-López G, Cañamero M, Mulero F, Pastor J, Martinez S, Romanos E, Mar Gonzalez-Barroso M, Rial E, Valverde AM, Bischoff JR, Serrano M. Ortega-Molina A, et al. Among authors: mulero f. Cell Metab. 2012 Mar 7;15(3):382-94. doi: 10.1016/j.cmet.2012.02.001. Cell Metab. 2012. PMID: 22405073 Free article.
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Maraver A, Fernández-Marcos PJ, Herranz D, Muñoz-Martin M, Gomez-Lopez G, Cañamero M, Mulero F, Megías D, Sanchez-Carbayo M, Shen J, Sanchez-Cespedes M, Palomero T, Ferrando A, Serrano M. Maraver A, et al. Among authors: mulero f. Cancer Cell. 2012 Aug 14;22(2):222-34. doi: 10.1016/j.ccr.2012.06.014. Cancer Cell. 2012. PMID: 22897852 Free PMC article.
K-RasV14I recapitulates Noonan syndrome in mice.
Hernández-Porras I, Fabbiano S, Schuhmacher AJ, Aicher A, Cañamero M, Cámara JA, Cussó L, Desco M, Heeschen C, Mulero F, Bustelo XR, Guerra C, Barbacid M. Hernández-Porras I, et al. Among authors: mulero f. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16395-400. doi: 10.1073/pnas.1418126111. Epub 2014 Oct 30. Proc Natl Acad Sci U S A. 2014. PMID: 25359213 Free PMC article.
Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage.
García-Beccaria M, Martínez P, Méndez-Pertuz M, Martínez S, Blanco-Aparicio C, Cañamero M, Mulero F, Ambrogio C, Flores JM, Megias D, Barbacid M, Pastor J, Blasco MA. García-Beccaria M, et al. Among authors: mulero f. EMBO Mol Med. 2015 Jul;7(7):930-49. doi: 10.15252/emmm.201404497. EMBO Mol Med. 2015. PMID: 25971796 Free PMC article.
Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.
de Lucas AG, Schuhmacher AJ, Oteo M, Romero E, Cámara JA, de Martino A, Arroyo AG, Morcillo MÁ, Squatrito M, Martinez-Torrecuadrada JL, Mulero F. de Lucas AG, et al. Among authors: mulero f. PLoS One. 2016 Jul 27;11(7):e0158634. doi: 10.1371/journal.pone.0158634. eCollection 2016. PLoS One. 2016. PMID: 27462980 Free PMC article.
66 results