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Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways.
Wojtas AM, Kang SS, Olley BM, Gatherer M, Shinohara M, Lozano PA, Liu CC, Kurti A, Baker KE, Dickson DW, Yue M, Petrucelli L, Bu G, Carare RO, Fryer JD. Wojtas AM, et al. Among authors: baker ke. Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6962-E6971. doi: 10.1073/pnas.1701137114. Epub 2017 Jul 12. Proc Natl Acad Sci U S A. 2017. PMID: 28701379 Free PMC article.
Astrocyte-derived clusterin suppresses amyloid formation in vivo.
Wojtas AM, Sens JP, Kang SS, Baker KE, Berry TJ, Kurti A, Daughrity L, Jansen-West KR, Dickson DW, Petrucelli L, Bu G, Liu CC, Fryer JD. Wojtas AM, et al. Among authors: baker ke. Mol Neurodegener. 2020 Nov 27;15(1):71. doi: 10.1186/s13024-020-00416-1. Mol Neurodegener. 2020. PMID: 33246484 Free PMC article.
Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation.
Wojtas AM, Carlomagno Y, Sens JP, Kang SS, Jensen TD, Kurti A, Baker KE, Berry TJ, Phillips VR, Castanedes MC, Awan A, DeTure M, De Castro CHF, Librero AL, Yue M, Daughrity L, Jansen-West KR, Cook CN, Dickson DW, Petrucelli L, Fryer JD. Wojtas AM, et al. Among authors: baker ke. Acta Neuropathol Commun. 2020 Dec 1;8(1):210. doi: 10.1186/s40478-020-01079-1. Acta Neuropathol Commun. 2020. PMID: 33261653 Free PMC article.
Lipocalin-2 protects the brain during inflammatory conditions.
Kang SS, Ren Y, Liu CC, Kurti A, Baker KE, Bu G, Asmann Y, Fryer JD. Kang SS, et al. Among authors: baker ke. Mol Psychiatry. 2018 Feb;23(2):344-350. doi: 10.1038/mp.2016.243. Epub 2017 Jan 10. Mol Psychiatry. 2018. PMID: 28070126 Free PMC article.
Advancing genomics to improve health equity.
Madden EB, Hindorff LA, Bonham VL, Akintobi TH, Burchard EG, Baker KE, Begay RL, Carpten JD, Cox NJ, Di Francesco V, Dillard DA, Fletcher FE, Fullerton SM, Garrison NA, Hammack-Aviran CM, Hiratsuka VY, Hildreth JEK, Horowitz CR, Hughes Halbert CA, Inouye M, Jackson A, Landry LG, Kittles RA, Leek JT, Limdi NA, Lockhart NC, Ofili EO, Pérez-Stable EJ, Sabatello M, Saulsberry L, Schools LE, Troyer JL, Wilfond BS, Wojcik GL, Cho JH, Lee SS, Green ED. Madden EB, et al. Among authors: baker ke. Nat Genet. 2024 May;56(5):752-757. doi: 10.1038/s41588-024-01711-z. Epub 2024 Apr 29. Nat Genet. 2024. PMID: 38684898 Free PMC article. Review.
Unsupervised machine learning models reveal predictive clinical markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation.
Wang W, Kumm ZT, Ho C, Zanesco-Fontes I, Texiera G, Reis RM, Martinetto H, Khan J, McCandless MG, Baker KE, Anderson MD, Chohan MO, Beyer S, Elder JB, Giglio P, Otero JJ. Wang W, et al. Among authors: baker ke. Neurooncol Adv. 2023 Nov 11;6(1):vdad140. doi: 10.1093/noajnl/vdad140. eCollection 2024 Jan-Dec. Neurooncol Adv. 2023. PMID: 38405202 Free PMC article.
90 results