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Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis.
Marsch E, Theelen TL, Demandt JA, Jeurissen M, van Gink M, Verjans R, Janssen A, Cleutjens JP, Meex SJ, Donners MM, Haenen GR, Schalkwijk CG, Dubois LJ, Lambin P, Mallat Z, Gijbels MJ, Heemskerk JW, Fisher EA, Biessen EA, Janssen BJ, Daemen MJ, Sluimer JC. Marsch E, et al. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2545-53. doi: 10.1161/ATVBAHA.114.304023. Epub 2014 Sep 25. Arterioscler Thromb Vasc Biol. 2014. PMID: 25256233
Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells.
van Gisbergen MW, Cebula M, Zhang J, Ottosson-Wadlund A, Dubois L, Lambin P, Tew KD, Townsend DM, Haenen GR, Drittij-Reijnders MJ, Saneyoshi H, Araki M, Shishido Y, Ito Y, Arnér ES, Abe H, Morgenstern R, Johansson K. van Gisbergen MW, et al. Mol Pharm. 2016 Jun 6;13(6):2010-25. doi: 10.1021/acs.molpharmaceut.6b00140. Epub 2016 Apr 28. Mol Pharm. 2016. PMID: 27093577 Free PMC article.
The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy.
van Kuijk SJ, Gieling RG, Niemans R, Lieuwes NG, Biemans R, Telfer BA, Haenen GR, Yaromina A, Lambin P, Dubois LJ, Williams KJ. van Kuijk SJ, et al. PLoS One. 2016 Aug 11;11(8):e0161040. doi: 10.1371/journal.pone.0161040. eCollection 2016. PLoS One. 2016. PMID: 27513947 Free PMC article.
206 results