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Structural Basis of Analog Specificity in PKG I and II.
Campbell JC, Henning P, Franz E, Sankaran B, Herberg FW, Kim C. Campbell JC, et al. Among authors: herberg fw. ACS Chem Biol. 2017 Sep 15;12(9):2388-2398. doi: 10.1021/acschembio.7b00369. Epub 2017 Aug 22. ACS Chem Biol. 2017. PMID: 28793191 Free PMC article.
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Huang GY, et al. Among authors: herberg fw. Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14. Structure. 2014. PMID: 24239458 Free PMC article.
Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress.
Kim JJ, Flueck C, Franz E, Sanabria-Figueroa E, Thompson E, Lorenz R, Bertinetti D, Baker DA, Herberg FW, Kim C. Kim JJ, et al. Among authors: herberg fw. PLoS Pathog. 2015 Feb 3;11(2):e1004639. doi: 10.1371/journal.ppat.1004639. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25646845 Free PMC article.
PKA-type I selective constrained peptide disruptors of AKAP complexes.
Wang Y, Ho TG, Franz E, Hermann JS, Smith FD, Hehnly H, Esseltine JL, Hanold LE, Murph MM, Bertinetti D, Scott JD, Herberg FW, Kennedy EJ. Wang Y, et al. Among authors: herberg fw. ACS Chem Biol. 2015 Jun 19;10(6):1502-10. doi: 10.1021/acschembio.5b00009. Epub 2015 Mar 25. ACS Chem Biol. 2015. PMID: 25765284 Free PMC article.
Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG).
VanSchouwen B, Selvaratnam R, Giri R, Lorenz R, Herberg FW, Kim C, Melacini G. VanSchouwen B, et al. Among authors: herberg fw. J Biol Chem. 2015 Nov 27;290(48):28631-41. doi: 10.1074/jbc.M115.685305. Epub 2015 Sep 14. J Biol Chem. 2015. PMID: 26370085 Free PMC article.
150 results