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Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
van Meeteren LA, Ruurs P, Christodoulou E, Goding JW, Takakusa H, Kikuchi K, Perrakis A, Nagano T, Moolenaar WH. van Meeteren LA, et al. Among authors: perrakis a. J Biol Chem. 2005 Jun 3;280(22):21155-61. doi: 10.1074/jbc.M413183200. Epub 2005 Mar 15. J Biol Chem. 2005. PMID: 15769751 Free article.
Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.
Hausmann J, Christodoulou E, Kasiem M, De Marco V, van Meeteren LA, Moolenaar WH, Axford D, Owen RL, Evans G, Perrakis A. Hausmann J, et al. Among authors: perrakis a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1130-5. doi: 10.1107/S1744309110032938. Epub 2010 Aug 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823545 Free PMC article.
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: perrakis a. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.
Autotaxin: structure-function and signaling.
Perrakis A, Moolenaar WH. Perrakis A, et al. J Lipid Res. 2014 Jun;55(6):1010-8. doi: 10.1194/jlr.R046391. Epub 2014 Feb 18. J Lipid Res. 2014. PMID: 24548887 Free PMC article. Review.
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Keune WJ, et al. Among authors: perrakis a. Nat Commun. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248. Nat Commun. 2016. PMID: 27075612 Free PMC article.
244 results