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Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation.
Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Jackson LE, et al. Among authors: goetzman es. Cancer Res. 2017 Nov 1;77(21):5795-5807. doi: 10.1158/0008-5472.CAN-17-1325. Epub 2017 Sep 7. Cancer Res. 2017. PMID: 28883002 Free PMC article.
Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES. Bharathi SS, et al. Among authors: goetzman es. J Biol Chem. 2013 Nov 22;288(47):33837-33847. doi: 10.1074/jbc.M113.510354. Epub 2013 Oct 11. J Biol Chem. 2013. PMID: 24121500 Free PMC article.
Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction.
Goetzman ES, Alcorn JF, Bharathi SS, Uppala R, McHugh KJ, Kosmider B, Chen R, Zuo YY, Beck ME, McKinney RW, Skilling H, Suhrie KR, Karunanidhi A, Yeasted R, Otsubo C, Ellis B, Tyurina YY, Kagan VE, Mallampalli RK, Vockley J. Goetzman ES, et al. J Biol Chem. 2014 Apr 11;289(15):10668-10679. doi: 10.1074/jbc.M113.540260. Epub 2014 Mar 3. J Biol Chem. 2014. PMID: 24591516 Free PMC article.
c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. Edmunds LR, et al. Among authors: goetzman es. J Biol Chem. 2014 Sep 5;289(36):25382-92. doi: 10.1074/jbc.M114.580662. Epub 2014 Jul 22. J Biol Chem. 2014. PMID: 25053415 Free PMC article.
Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency.
Schiff M, Haberberger B, Xia C, Mohsen AW, Goetzman ES, Wang Y, Uppala R, Zhang Y, Karunanidhi A, Prabhu D, Alharbi H, Prochownik EV, Haack T, Häberle J, Munnich A, Rötig A, Taylor RW, Nicholls RD, Kim JJ, Prokisch H, Vockley J. Schiff M, et al. Among authors: goetzman es. Hum Mol Genet. 2015 Jun 1;24(11):3238-47. doi: 10.1093/hmg/ddv074. Epub 2015 Feb 26. Hum Mol Genet. 2015. PMID: 25721401 Free PMC article.
Long-chain Acylcarnitines Reduce Lung Function by Inhibiting Pulmonary Surfactant.
Otsubo C, Bharathi S, Uppala R, Ilkayeva OR, Wang D, McHugh K, Zou Y, Wang J, Alcorn JF, Zuo YY, Hirschey MD, Goetzman ES. Otsubo C, et al. Among authors: goetzman es. J Biol Chem. 2015 Sep 25;290(39):23897-904. doi: 10.1074/jbc.M115.655837. Epub 2015 Aug 3. J Biol Chem. 2015. PMID: 26240137 Free PMC article.
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.
Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Wang H, et al. Among authors: goetzman es. J Biol Chem. 2016 Dec 16;291(51):26241-26251. doi: 10.1074/jbc.M116.754218. Epub 2016 Oct 13. J Biol Chem. 2016. PMID: 27738108 Free PMC article.
Aspirin increases mitochondrial fatty acid oxidation.
Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES. Uppala R, et al. Among authors: goetzman es. Biochem Biophys Res Commun. 2017 Jan 8;482(2):346-351. doi: 10.1016/j.bbrc.2016.11.066. Epub 2016 Nov 14. Biochem Biophys Res Commun. 2017. PMID: 27856258 Free PMC article.
72 results