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Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation.
Hernández-Rodas MC, Valenzuela R, Echeverría F, Rincón-Cervera MÁ, Espinosa A, Illesca P, Muñoz P, Corbari A, Romero N, Gonzalez-Mañan D, Videla LA. Hernández-Rodas MC, et al. Mol Nutr Food Res. 2017 Dec;61(12). doi: 10.1002/mnfr.201700479. Epub 2017 Nov 13. Mol Nutr Food Res. 2017. PMID: 28940752
Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects on fatty acid composition in liver and extrahepatic tissues.
Rincón-Cervera MA, Valenzuela R, Hernandez-Rodas MC, Marambio M, Espinosa A, Mayer S, Romero N, Barrera M Sc C, Valenzuela A, Videla LA. Rincón-Cervera MA, et al. Nutrition. 2016 Nov-Dec;32(11-12):1254-67. doi: 10.1016/j.nut.2016.04.006. Epub 2016 May 17. Nutrition. 2016. PMID: 27346714
Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice.
Valenzuela R, Echeverria F, Ortiz M, Rincón-Cervera MÁ, Espinosa A, Hernandez-Rodas MC, Illesca P, Valenzuela A, Videla LA. Valenzuela R, et al. Lipids Health Dis. 2017 Apr 11;16(1):64. doi: 10.1186/s12944-017-0450-5. Lipids Health Dis. 2017. PMID: 28395666 Free PMC article.
Adding a purple corn extract in rats supplemented with chia oil decreases gene expression of SREBP-1c and retains Δ5 and Δ6 hepatic desaturase activity, unmodified the hepatic lipid profile.
Reyna Gallegos S, Torres Arrunátegui G, Valenzuela R, Rincón-Cervera MÁ, Villanueva Espinoza ME. Reyna Gallegos S, et al. Prostaglandins Leukot Essent Fatty Acids. 2018 May;132:1-7. doi: 10.1016/j.plefa.2018.03.005. Epub 2018 Mar 28. Prostaglandins Leukot Essent Fatty Acids. 2018. PMID: 29735017
20 results