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β-Arrestin2 mediates progression of murine primary myelofibrosis.
Rein LA, Wisler JW, Kim J, Theriot B, Huang L, Price T, Yang H, Chen M, Chen W, Sipkins D, Fedoriw Y, Walker JK, Premont RT, Lefkowitz RJ. Rein LA, et al. Among authors: wisler jw. JCI Insight. 2017 Dec 21;2(24):e98094. doi: 10.1172/jci.insight.98094. JCI Insight. 2017. PMID: 29263312 Free PMC article.
Recent developments in biased agonism.
Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Wisler JW, et al. Curr Opin Cell Biol. 2014 Apr;27:18-24. doi: 10.1016/j.ceb.2013.10.008. Epub 2013 Nov 20. Curr Opin Cell Biol. 2014. PMID: 24680426 Free PMC article. Review.
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. Drake MT, et al. Among authors: wisler jw. J Biol Chem. 2008 Feb 29;283(9):5669-76. doi: 10.1074/jbc.M708118200. Epub 2007 Dec 17. J Biol Chem. 2008. PMID: 18086673 Free article.
Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.
Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, Alam SM, Sullenger BA, Lefkowitz RJ. Kahsai AW, et al. Among authors: wisler jw. Nat Chem Biol. 2016 Sep;12(9):709-16. doi: 10.1038/nchembio.2126. Epub 2016 Jul 11. Nat Chem Biol. 2016. PMID: 27398998 Free PMC article.
19 results