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Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity.
Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Parmar G, Divoux A, Kapoor N, Yi F, Cornnell H, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM. Whytock KL, et al. Among authors: harper me. Am J Physiol Endocrinol Metab. 2023 Oct 1;325(4):E291-E302. doi: 10.1152/ajpendo.00143.2023. Epub 2023 Aug 16. Am J Physiol Endocrinol Metab. 2023. PMID: 37584609
GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Wang D, Townsend LK, DesOrmeaux GJ, Frangos SM, Batchuluun B, Dumont L, Kuhre RE, Ahmadi E, Hu S, Rebalka IA, Gautam J, Jabile MJT, Pileggi CA, Rehal S, Desjardins EM, Tsakiridis EE, Lally JSV, Juracic ES, Tupling AR, Gerstein HC, Paré G, Tsakiridis T, Harper ME, Hawke TJ, Speakman JR, Blondin DP, Holloway GP, Jørgensen SB, Steinberg GR. Wang D, et al. Among authors: harper me. Nature. 2023 Jul;619(7968):143-150. doi: 10.1038/s41586-023-06249-4. Epub 2023 Jun 28. Nature. 2023. PMID: 37380764 Free PMC article.
16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.
Béland-Millar A, Kirby A, Truong Y, Ouellette J, Yandiev S, Bouyakdan K, Pileggi C, Naz S, Yin M, Carrier M, Kotchetkov P, St-Pierre MK, Tremblay MÈ, Courchet J, Harper ME, Alquier T, Messier C, Shuhendler AJ, Lacoste B. Béland-Millar A, et al. Among authors: harper me. Cell Rep. 2023 May 30;42(5):112485. doi: 10.1016/j.celrep.2023.112485. Epub 2023 May 6. Cell Rep. 2023. PMID: 37149866 Free article.
311 results