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Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers.
Rashmi R, Jayachandran K, Zhang J, Menon V, Muhammad N, Zahner M, Ruiz F, Zhang S, Cho K, Wang Y, Huang X, Huang Y, McCormick ML, Rogers BE, Spitz DR, Patti GJ, Schwarz JK. Rashmi R, et al. Among authors: huang x, huang y. Mol Cancer Ther. 2020 Dec;19(12):2465-2475. doi: 10.1158/1535-7163.MCT-20-0271. Epub 2020 Oct 21. Mol Cancer Ther. 2020. PMID: 33087507 Free PMC article.
Lactate metabolism is associated with mammalian mitochondria.
Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ. Chen YJ, et al. Among authors: huang x. Nat Chem Biol. 2016 Nov;12(11):937-943. doi: 10.1038/nchembio.2172. Epub 2016 Sep 12. Nat Chem Biol. 2016. PMID: 27618187 Free PMC article.
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Puchalska P, Martin SE, Huang X, Lengfeld JE, Daniel B, Graham MJ, Han X, Nagy L, Patti GJ, Crawford PA. Puchalska P, et al. Among authors: huang x. Cell Metab. 2019 Feb 5;29(2):383-398.e7. doi: 10.1016/j.cmet.2018.10.015. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449686 Free PMC article.
Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia.
Cotter DG, Ercal B, Huang X, Leid JM, d'Avignon DA, Graham MJ, Dietzen DJ, Brunt EM, Patti GJ, Crawford PA. Cotter DG, et al. Among authors: huang x. J Clin Invest. 2014 Dec;124(12):5175-90. doi: 10.1172/JCI76388. Epub 2014 Oct 27. J Clin Invest. 2014. PMID: 25347470 Free PMC article.
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