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Lactate metabolism is associated with mammalian mitochondria.
Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ. Chen YJ, et al. Among authors: patti gj. Nat Chem Biol. 2016 Nov;12(11):937-943. doi: 10.1038/nchembio.2172. Epub 2016 Sep 12. Nat Chem Biol. 2016. PMID: 27618187 Free PMC article.
Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers.
Rashmi R, Jayachandran K, Zhang J, Menon V, Muhammad N, Zahner M, Ruiz F, Zhang S, Cho K, Wang Y, Huang X, Huang Y, McCormick ML, Rogers BE, Spitz DR, Patti GJ, Schwarz JK. Rashmi R, et al. Among authors: patti gj. Mol Cancer Ther. 2020 Dec;19(12):2465-2475. doi: 10.1158/1535-7163.MCT-20-0271. Epub 2020 Oct 21. Mol Cancer Ther. 2020. PMID: 33087507 Free PMC article.
GAS6-AXL Inhibition by AVB-500 Overcomes Resistance to Paclitaxel in Endometrial Cancer by Decreasing Tumor Cell Glycolysis.
Bruce SF, Cho K, Noia H, Lomonosova E, Stock EC, Oplt A, Blachut B, Mullen MM, Kuroki LM, Hagemann AR, McCourt CK, Thaker PH, Khabele D, Powell MA, Mutch DG, Shriver LP, Patti GJ, Fuh KC. Bruce SF, et al. Among authors: patti gj. Mol Cancer Ther. 2022 Aug 2;21(8):1348-1359. doi: 10.1158/1535-7163.MCT-21-0704. Mol Cancer Ther. 2022. PMID: 35588308 Free PMC article.
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment.
Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, Tinkum KL, Gass H, Nunez E, Spitz DR, Chinnaiyan P, Schaefer J, Patti GJ, Graham MS, Mauguen A, Grkovski M, Dunphy MP, Krebs S, Luo J, Rubin JB, Ippolito JE. Sponagel J, et al. Among authors: patti gj. Med. 2022 Nov 11;3(11):792-811.e12. doi: 10.1016/j.medj.2022.08.005. Epub 2022 Sep 14. Med. 2022. PMID: 36108629 Free PMC article.
151 results