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Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.
Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H. Sioofy-Khojine AB, et al. Diabetologia. 2018 May;61(5):1193-1202. doi: 10.1007/s00125-018-4561-y. Epub 2018 Feb 5. Diabetologia. 2018. PMID: 29404673
Serum proteomes distinguish children developing type 1 diabetes in a cohort with HLA-conferred susceptibility.
Moulder R, Bhosale SD, Erkkilä T, Laajala E, Salmi J, Nguyen EV, Kallionpää H, Mykkänen J, Vähä-Mäkilä M, Hyöty H, Veijola R, Ilonen J, Simell T, Toppari J, Knip M, Goodlett DR, Lähdesmäki H, Simell O, Lahesmaa R. Moulder R, et al. Diabetes. 2015 Jun;64(6):2265-78. doi: 10.2337/db14-0983. Epub 2015 Jan 23. Diabetes. 2015. PMID: 25616278
Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.
Uusitalo U, Liu X, Yang J, Aronsson CA, Hummel S, Butterworth M, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, Norris JM, Virtanen SM; TEDDY Study Group. Uusitalo U, et al. JAMA Pediatr. 2016 Jan;170(1):20-8. doi: 10.1001/jamapediatrics.2015.2757. JAMA Pediatr. 2016. PMID: 26552054 Free PMC article.
Reduced β-cell function in early preclinical type 1 diabetes.
Koskinen MK, Helminen O, Matomäki J, Aspholm S, Mykkänen J, Mäkinen M, Simell V, Vähä-Mäkilä M, Simell T, Ilonen J, Knip M, Veijola R, Toppari J, Simell O. Koskinen MK, et al. Eur J Endocrinol. 2016 Mar;174(3):251-9. doi: 10.1530/EJE-15-0674. Epub 2015 Nov 30. Eur J Endocrinol. 2016. PMID: 26620391 Free PMC article.
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study.
Törn C, Liu X, Hagopian W, Lernmark Å, Simell O, Rewers M, Ziegler AG, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, Rich SS, She JX, Sharma A, Steck A, Krischer J; TEDDY Study Group. Törn C, et al. Sci Rep. 2016 Jun 16;6:27887. doi: 10.1038/srep27887. Sci Rep. 2016. PMID: 27306948 Free PMC article. Clinical Trial.
Natural Development of Antibodies against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Protein Antigens during the First 13 Years of Life.
Borges IC, Andrade DC, Cardoso MR, Toppari J, Vähä-Mäkilä M, Ilonen J, Knip M, Hyöty H, Veijola R, Simell O, Jartti T, Käyhty H, Ruuskanen O, Nascimento-Carvalho CM. Borges IC, et al. Clin Vaccine Immunol. 2016 Nov 4;23(11):878-883. doi: 10.1128/CVI.00341-16. Print 2016 Nov. Clin Vaccine Immunol. 2016. PMID: 27581439 Free PMC article.
Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity.
Lundgren M, Steed LJ, Tamura R, Jonsdottir B, Gesualdo P, Crouch C, Sjöberg M, Hansson G, Hagopian WA, Ziegler AG, Rewers MJ, Lernmark Å, Toppari J, She JX, Akolkar B, Krischer JP, Haller MJ, Elding Larsson H; TEDDY Study Group. Lundgren M, et al. BMC Pediatr. 2017 May 16;17(1):127. doi: 10.1186/s12887-017-0884-y. BMC Pediatr. 2017. PMID: 28511706 Free PMC article.
Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study.
Köhler M, Beyerlein A, Vehik K, Greven S, Umlauf N, Lernmark Å, Hagopian WA, Rewers M, She JX, Toppari J, Akolkar B, Krischer JP, Bonifacio E, Ziegler AG; TEDDY study group. Köhler M, et al. Acta Diabetol. 2017 Nov;54(11):1009-1017. doi: 10.1007/s00592-017-1033-7. Epub 2017 Aug 30. Acta Diabetol. 2017. PMID: 28856522 Free PMC article.
50 results