Tarozzi A - Search Results

1

Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.

Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C Jr. Dias Viegas FP, et al. Among authors: tarozzi a. Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29421570

2

[Insulin receptors: the in vitro effect of oral hypoglycemic agents].

Zandomeneghi R, Tarozzi A, Sticchi G, Cristani A. Zandomeneghi R, et al. Among authors: tarozzi a. Boll Soc Ital Biol Sper. 1981 Apr 15;57(7):730-6. Boll Soc Ital Biol Sper. 1981. PMID: 7023503 Italian. No abstract available.

3

Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds.

Antonello A, Hrelia P, Leonardi A, Marucci G, Rosini M, Tarozzi A, Tumiatti V, Melchiorre C. Antonello A, et al. Among authors: tarozzi a. J Med Chem. 2005 Jan 13;48(1):28-31. doi: 10.1021/jm049153d. J Med Chem. 2005. PMID: 15633998

4

Rational approach to discover multipotent anti-Alzheimer drugs.

Rosini M, Andrisano V, Bartolini M, Bolognesi ML, Hrelia P, Minarini A, Tarozzi A, Melchiorre C. Rosini M, et al. Among authors: tarozzi a. J Med Chem. 2005 Jan 27;48(2):360-3. doi: 10.1021/jm049112h. J Med Chem. 2005. PMID: 15658850

5

Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors.

Rosini M, Mancini F, Tarozzi A, Colizzi F, Andrisano V, Bolognesi ML, Hrelia P, Melchiorre C. Rosini M, et al. Among authors: tarozzi a. Bioorg Med Chem. 2006 Dec 1;14(23):7846-53. doi: 10.1016/j.bmc.2006.07.059. Bioorg Med Chem. 2006. PMID: 16908175

6

Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects.

Antonello A, Tarozzi A, Morroni F, Cavalli A, Rosini M, Hrelia P, Bolognesi ML, Melchiorre C. Antonello A, et al. Among authors: tarozzi a. J Med Chem. 2006 Nov 16;49(23):6642-5. doi: 10.1021/jm0608762. J Med Chem. 2006. PMID: 17154492

7

Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.

Bolognesi ML, Banzi R, Bartolini M, Cavalli A, Tarozzi A, Andrisano V, Minarini A, Rosini M, Tumiatti V, Bergamini C, Fato R, Lenaz G, Hrelia P, Cattaneo A, Recanatini M, Melchiorre C. Bolognesi ML, et al. Among authors: tarozzi a. J Med Chem. 2007 Oct 4;50(20):4882-97. doi: 10.1021/jm070559a. Epub 2007 Sep 13. J Med Chem. 2007. PMID: 17850125

8

Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity.

Rizzo S, Rivière C, Piazzi L, Bisi A, Gobbi S, Bartolini M, Andrisano V, Morroni F, Tarozzi A, Monti JP, Rampa A. Rizzo S, et al. Among authors: tarozzi a. J Med Chem. 2008 May 22;51(10):2883-6. doi: 10.1021/jm8002747. Epub 2008 Apr 18. J Med Chem. 2008. PMID: 18419109

9

Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.

Rosini M, Simoni E, Bartolini M, Cavalli A, Ceccarini L, Pascu N, McClymont DW, Tarozzi A, Bolognesi ML, Minarini A, Tumiatti V, Andrisano V, Mellor IR, Melchiorre C. Rosini M, et al. Among authors: tarozzi a. J Med Chem. 2008 Aug 14;51(15):4381-4. doi: 10.1021/jm800577j. Epub 2008 Jul 8. J Med Chem. 2008. PMID: 18605718

10

Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.

Simoni E, Bergamini C, Fato R, Tarozzi A, Bains S, Motterlini R, Cavalli A, Bolognesi ML, Minarini A, Hrelia P, Lenaz G, Rosini M, Melchiorre C. Simoni E, et al. Among authors: tarozzi a. J Med Chem. 2010 Oct 14;53(19):7264-8. doi: 10.1021/jm100637k. J Med Chem. 2010. PMID: 20831222

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