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Neutrophils drive type I interferon production and autoantibodies in patients with Wiskott-Aldrich syndrome.
Cervantes-Luevano KE, Caronni N, Castiello MC, Fontana E, Piperno GM, Naseem A, Uva P, Bosticardo M, Marcovecchio GE, Notarangelo LD, Cicalese MP, Aiuti A, Villa A, Benvenuti F. Cervantes-Luevano KE, et al. Among authors: aiuti a. J Allergy Clin Immunol. 2018 Nov;142(5):1605-1617.e4. doi: 10.1016/j.jaci.2017.11.063. Epub 2018 Feb 13. J Allergy Clin Immunol. 2018. PMID: 29447842 Free PMC article.
Clinical improvement and normalized Th1 cytokine profile in early and long-term interferon-alpha treatment in a suspected case of hyper-IgE syndrome.
Benninghoff U, Cattaneo F, Aiuti A, Flores-D'Arcais A, Gelmetti C, Viscardi M, Callegaro L, Mirolo M, Ambrosi A, Roncarolo MG, Bacchetta R. Benninghoff U, et al. Among authors: aiuti a. Pediatr Allergy Immunol. 2008 Sep;19(6):564-8. doi: 10.1111/j.1399-3038.2007.00683.x. Pediatr Allergy Immunol. 2008. PMID: 18844858
Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.
Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A. Marangoni F, et al. Among authors: aiuti a. Mol Ther. 2009 Jun;17(6):1073-82. doi: 10.1038/mt.2009.31. Epub 2009 Mar 3. Mol Ther. 2009. PMID: 19259069 Free PMC article.
The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function.
Locci M, Draghici E, Marangoni F, Bosticardo M, Catucci M, Aiuti A, Cancrini C, Marodi L, Espanol T, Bredius RG, Thrasher AJ, Schulz A, Litzman J, Roncarolo MG, Casorati G, Dellabona P, Villa A. Locci M, et al. Among authors: aiuti a. J Exp Med. 2009 Apr 13;206(4):735-42. doi: 10.1084/jem.20081773. Epub 2009 Mar 23. J Exp Med. 2009. PMID: 19307326 Free PMC article.
292 results