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Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.
Huang LH, Melton EM, Li H, Sohn P, Jung D, Tsai CY, Ma T, Sano H, Ha H, Friedline RH, Kim JK, Usherwood E, Chang CCY, Chang TY. Huang LH, et al. Among authors: friedline rh. Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E340-E356. doi: 10.1152/ajpendo.00174.2017. Epub 2018 Mar 13. Am J Physiol Endocrinol Metab. 2018. PMID: 29533741 Free PMC article.
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.
Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee CG, Elias JA, Kim JK. Hong EG, et al. Among authors: friedline rh. Diabetes. 2009 Nov;58(11):2525-35. doi: 10.2337/db08-1261. Epub 2009 Aug 18. Diabetes. 2009. PMID: 19690064 Free PMC article.
TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.
Zhang Z, Zhang W, Jung DY, Ko HJ, Lee Y, Friedline RH, Lee E, Jun J, Ma Z, Kim F, Tsitsilianos N, Chapman K, Morrison A, Cooper MP, Miller BA, Kim JK. Zhang Z, et al. Among authors: friedline rh. Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E807-16. doi: 10.1152/ajpendo.00239.2011. Epub 2012 Jan 24. Am J Physiol Endocrinol Metab. 2012. PMID: 22275755 Free PMC article.
Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.
Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Nat Methods. 2012 Mar 4;9(4):403-9. doi: 10.1038/nmeth.1903. Nat Methods. 2012. PMID: 22388288 Free PMC article.
Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice.
Jung DY, Ko HJ, Lichtman EI, Lee E, Lawton E, Ong H, Yu K, Azuma Y, Friedline RH, Lee KW, Kim JK. Jung DY, et al. Among authors: friedline rh. Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E964-76. doi: 10.1152/ajpendo.00462.2012. Epub 2013 Mar 12. Am J Physiol Endocrinol Metab. 2013. PMID: 23482446 Free PMC article.
Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice.
Hong EG, Kim BW, Jung DY, Kim JH, Yu T, Seixas Da Silva W, Friedline RH, Bianco SD, Seslar SP, Wakimoto H, Berul CI, Russell KS, Lee KW, Larsen PR, Bianco AC, Kim JK. Hong EG, et al. Among authors: friedline rh. Endocrinology. 2013 Oct;154(10):3937-46. doi: 10.1210/en.2012-2261. Epub 2013 Jul 16. Endocrinology. 2013. PMID: 23861374 Free PMC article.
KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.
Jung DY, Chalasani U, Pan N, Friedline RH, Prosdocimo DA, Nam M, Azuma Y, Maganti R, Yu K, Velagapudi A, O'Sullivan-Murphy B, Sartoretto JL, Jain MK, Cooper MP, Urano F, Kim JK, Gray S. Jung DY, et al. Among authors: friedline rh. PLoS One. 2013 Oct 22;8(10):e77851. doi: 10.1371/journal.pone.0077851. eCollection 2013. PLoS One. 2013. PMID: 24167585 Free PMC article.
39 results