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Aldehyde oxidase activity in fresh human skin.
Manevski N, Balavenkatraman KK, Bertschi B, Swart P, Walles M, Camenisch G, Schiller H, Kretz O, Ling B, Wettstein R, Schaefer DJ, Pognan F, Wolf A, Litherland K. Manevski N, et al. Among authors: camenisch g. Drug Metab Dispos. 2014 Dec;42(12):2049-57. doi: 10.1124/dmd.114.060368. Epub 2014 Sep 23. Drug Metab Dispos. 2014. PMID: 25249692
Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
Manevski N, Swart P, Balavenkatraman KK, Bertschi B, Camenisch G, Kretz O, Schiller H, Walles M, Ling B, Wettstein R, Schaefer DJ, Itin P, Ashton-Chess J, Pognan F, Wolf A, Litherland K. Manevski N, et al. Among authors: camenisch g. Drug Metab Dispos. 2015 Jan;43(1):126-39. doi: 10.1124/dmd.114.060350. Epub 2014 Oct 22. Drug Metab Dispos. 2015. PMID: 25339109
Assessment of the pulmonary CYP1A1 metabolism of mavoglurant (AFQ056) in rat.
Yilmaz Y, Umehara K, Williams G, Faller T, Schiller H, Walles M, Kraehenbuehl S, Camenisch G, Manevski N. Yilmaz Y, et al. Among authors: camenisch g. Xenobiotica. 2018 Aug;48(8):793-803. doi: 10.1080/00498254.2017.1373311. Epub 2017 Sep 29. Xenobiotica. 2018. PMID: 28879796
Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism.
Wang-Lakshman L, Miao Z, Wang L, Gu H, Kagan M, Gu J, McNamara E, Walles M, Woessner R, Camenisch G, Einolf HJ, Chen J. Wang-Lakshman L, et al. Among authors: camenisch g. Drug Metab Dispos. 2021 Jul;49(7):548-562. doi: 10.1124/dmd.120.000349. Epub 2021 May 5. Drug Metab Dispos. 2021. PMID: 33952610 Clinical Trial.
102 results