Mackay AR - Search Results

1

The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII.

Farina AR, Cappabianca L, Ruggeri P, Gneo L, Pellegrini C, Fargnoli MC, Mackay AR. Farina AR, et al. Among authors: mackay ar. J Exp Clin Cancer Res. 2018 Jun 18;37(1):119. doi: 10.1186/s13046-018-0786-3. J Exp Clin Cancer Res. 2018. PMID: 29914559 Free PMC article. Review.

2

Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site.

Cappabianca L, Farina AR, Tacconelli A, Mantovani R, Gulino A, Mackay AR. Cappabianca L, et al. Among authors: mackay ar. Exp Cell Res. 2003 Jun 10;286(2):209-18. doi: 10.1016/s0014-4827(03)00072-7. Exp Cell Res. 2003. PMID: 12749850

3

The alternative TrkAIII splice variant targets the centrosome and promotes genetic instability.

Farina AR, Tacconelli A, Cappabianca L, Cea G, Panella S, Chioda A, Romanelli A, Pedone C, Gulino A, Mackay AR. Farina AR, et al. Among authors: mackay ar. Mol Cell Biol. 2009 Sep;29(17):4812-30. doi: 10.1128/MCB.00352-09. Epub 2009 Jun 29. Mol Cell Biol. 2009. PMID: 19564412 Free PMC article.

4

Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression.

Farina AR, Mackay AR. Farina AR, et al. Among authors: mackay ar. Cancers (Basel). 2014 Jan 27;6(1):240-96. doi: 10.3390/cancers6010240. Cancers (Basel). 2014. PMID: 24473089 Free PMC article.

5

Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity.

Farina AR, Cappabianca L, Ruggeri P, Gneo L, Maccarone R, Mackay AR. Farina AR, et al. Among authors: mackay ar. Oncotarget. 2015 Nov 3;6(34):35636-51. doi: 10.18632/oncotarget.5802. Oncotarget. 2015. PMID: 26415233 Free PMC article.

6

TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.

Gneo L, Ruggeri P, Cappabianca L, Farina AR, Di Ianni N, Mackay AR. Gneo L, et al. Among authors: mackay ar. Oncotarget. 2016 Dec 6;7(49):80820-80841. doi: 10.18632/oncotarget.13098. Oncotarget. 2016. PMID: 27821809 Free PMC article.

7

TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation.

Farina AR, Cappabianca L, Gneo L, Ruggeri P, Mackay AR. Farina AR, et al. Among authors: mackay ar. Oncotarget. 2017 Dec 22;9(9):8368-8390. doi: 10.18632/oncotarget.23618. eCollection 2018 Feb 2. Oncotarget. 2017. PMID: 29492201 Free PMC article.

8

A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target.

Cappabianca L, Guadagni S, Maccarone R, Sebastiano M, Chiominto A, Farina AR, Mackay AR. Cappabianca L, et al. Among authors: mackay ar. J Exp Clin Cancer Res. 2019 Oct 22;38(1):424. doi: 10.1186/s13046-019-1425-3. J Exp Clin Cancer Res. 2019. PMID: 31640749 Free PMC article.

9

Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma.

Cappabianca L, Farina AR, Di Marcotullio L, Infante P, De Simone D, Sebastiano M, Mackay AR. Cappabianca L, et al. Among authors: mackay ar. J Exp Clin Cancer Res. 2019 Dec 5;38(1):482. doi: 10.1186/s13046-019-1481-8. J Exp Clin Cancer Res. 2019. PMID: 31805994 Free PMC article.

10

Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer.

Farina AR, Cappabianca L, Sebastiano M, Zelli V, Guadagni S, Mackay AR. Farina AR, et al. Among authors: mackay ar. J Exp Clin Cancer Res. 2020 Jun 15;39(1):110. doi: 10.1186/s13046-020-01616-9. J Exp Clin Cancer Res. 2020. PMID: 32536347 Free PMC article. Review.

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