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Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology and Pharmacology.
CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):442-452. doi: 10.1002/psp4.12304. Epub 2018 Jun 19.
CPT Pharmacometrics Syst Pharmacol. 2018.
PMID: 29920993
Free PMC article.
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat.
Abrams R, Kaddi CD, Tao M, Leiser RJ, Simoni G, Reali F, Tolsma J, Jasper P, van Rijn Z, Li J, Niesner B, Barrett JS, Marchetti L, Peterschmitt MJ, Azer K, Neves-Zaph S.
Abrams R, et al. Among authors: van rijn z.
CPT Pharmacometrics Syst Pharmacol. 2020 Jul;9(7):374-383. doi: 10.1002/psp4.12506. Epub 2020 Jun 19.
CPT Pharmacometrics Syst Pharmacol. 2020.
PMID: 32558397
Free PMC article.
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