Pahnke J - Search Results

1

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.

Storck SE, Hartz AMS, Bernard J, Wolf A, Kachlmeier A, Mahringer A, Weggen S, Pahnke J, Pietrzik CU. Storck SE, et al. Among authors: pahnke j. Brain Behav Immun. 2018 Oct;73:21-33. doi: 10.1016/j.bbi.2018.07.017. Epub 2018 Jul 21. Brain Behav Immun. 2018. PMID: 30041013 Free PMC article.

2

The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.

Vogelgesang S, Warzok RW, Cascorbi I, Kunert-Keil C, Schroeder E, Kroemer HK, Siegmund W, Walker LC, Pahnke J. Vogelgesang S, et al. Among authors: pahnke j. Curr Alzheimer Res. 2004 May;1(2):121-5. doi: 10.2174/1567205043332225. Curr Alzheimer Res. 2004. PMID: 15975076 Free PMC article.

3

Cerebral ABC transporter-common mechanisms may modulate neurodegenerative diseases and depression in elderly subjects.

Pahnke J, Fröhlich C, Paarmann K, Krohn M, Bogdanovic N, Årsland D, Winblad B. Pahnke J, et al. Arch Med Res. 2014 Nov;45(8):738-43. doi: 10.1016/j.arcmed.2014.10.010. Epub 2014 Nov 11. Arch Med Res. 2014. PMID: 25446622

4

Accumulation of murine amyloid-β mimics early Alzheimer's disease.

Krohn M, Bracke A, Avchalumov Y, Schumacher T, Hofrichter J, Paarmann K, Fröhlich C, Lange C, Brüning T, von Bohlen Und Halbach O, Pahnke J. Krohn M, et al. Among authors: pahnke j. Brain. 2015 Aug;138(Pt 8):2370-82. doi: 10.1093/brain/awv137. Epub 2015 May 18. Brain. 2015. PMID: 25991605

5

Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.

Wanek T, Römermann K, Mairinger S, Stanek J, Sauberer M, Filip T, Traxl A, Kuntner C, Pahnke J, Bauer F, Erker T, Löscher W, Müller M, Langer O. Wanek T, et al. Among authors: pahnke j. Mol Pharm. 2015 Sep 8;12(9):3214-25. doi: 10.1021/acs.molpharmaceut.5b00168. Epub 2015 Aug 3. Mol Pharm. 2015. PMID: 26202880 Free PMC article.

6

Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula.

Bernstein HG, Hildebrandt J, Dobrowolny H, Steiner J, Bogerts B, Pahnke J. Bernstein HG, et al. Among authors: pahnke j. Schizophr Res. 2016 Nov;177(1-3):52-58. doi: 10.1016/j.schres.2016.02.036. Epub 2016 Mar 3. Schizophr Res. 2016. PMID: 26948503

7

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice.

Steffen J, Krohn M, Schwitlick C, Brüning T, Paarmann K, Pietrzik CU, Biverstål H, Jansone B, Langer O, Pahnke J. Steffen J, et al. Among authors: pahnke j. Acta Neuropathol Commun. 2017 Jun 20;5(1):49. doi: 10.1186/s40478-017-0448-2. Acta Neuropathol Commun. 2017. PMID: 28637503 Free PMC article.

8

ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier.

Lamartinière Y, Boucau MC, Dehouck L, Krohn M, Pahnke J, Candela P, Gosselet F, Fenart L. Lamartinière Y, et al. Among authors: pahnke j. J Alzheimers Dis. 2018;64(4):1195-1211. doi: 10.3233/JAD-170883. J Alzheimers Dis. 2018. PMID: 30010117

9

Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET.

Zoufal V, Wanek T, Krohn M, Mairinger S, Filip T, Sauberer M, Stanek J, Pekar T, Bauer M, Pahnke J, Langer O. Zoufal V, et al. Among authors: pahnke j. J Cereb Blood Flow Metab. 2020 Jan;40(1):150-162. doi: 10.1177/0271678X18806640. Epub 2018 Oct 24. J Cereb Blood Flow Metab. 2020. PMID: 30354871 Free PMC article.

10

Imaging P-Glycoprotein Induction at the Blood-Brain Barrier of a β-Amyloidosis Mouse Model with ¹¹C-Metoclopramide PET.

Zoufal V, Mairinger S, Brackhan M, Krohn M, Filip T, Sauberer M, Stanek J, Wanek T, Tournier N, Bauer M, Pahnke J, Langer O. Zoufal V, et al. Among authors: pahnke j. J Nucl Med. 2020 Jul;61(7):1050-1057. doi: 10.2967/jnumed.119.237198. Epub 2019 Dec 5. J Nucl Med. 2020. PMID: 31806767 Free PMC article.

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